Results 111 to 120 of about 6,249,163 (357)

In pursuit of β-amino α-nitro β-trifluoromethyl ketones: nitro-Mannich vs Mannich-type reactions [PDF]

, 2017
The reactivity of alfa-nitro ketones with trifluoromethyl aldimines is studied for the first time. While under nitro-Mannich conditions only the facial stereoselectivity can be controlled, organocatalysed Mannich-type reactions allowed a complete control
Ballini, Ballini, Ballini, Ballini, Bhadury, Carroccia, Carroccia, Chen, Claridge, Córdova, Dighe, Dinér, Donslund, Fioravanti, Fioravanti, Fioravanti, Fioravanti, Fioravanti, Gao, Ghosh, Hatano, Hurd, Ibrahem, Ilies, Kano, Kano, Kelly, Kobayashi, Kokotos, Levy, Merino, Mitsumori, Moteki, Nguyen, Nie, Noble, Parise, Parise, Pelagalli, Stach, Walaszek, Yang, Yin, Zhang, Zhang, Zheng   +45 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Synthesis of the fatty esters of solketal and glycerol-formal: biobased specialty chemicals [PDF]

, 2015
The caprylic, lauric, palmitic and stearic esters of solketal and glycerol formal were synthesized with high selectivity and yields by a solvent-free acid catalyzed procedure.
Perosa, Alvise, Andrea Moraschini, Selva, Maurizio, Noè, Marco   +3 more
core   +7 more sources

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Solvent free model for self-assembling fluid bilayer membranes: Stabilization of the fluid phase based on broad attractive tail potentials

, 2005
We present a simple and highly adaptable method for simulating coarse-grained lipid membranes without explicit solvent. Lipids are represented by one head-bead and two tail-beads, with the interaction between tails being of key importance in stabilizing ...
Helfrich W., Ira R. Cooke, Lipowsky R., Markus Deserno, Seifert U.   +4 more
core   +1 more source

Invariom-model refinement and Hirshfeld surface analysis of well-ordered solvent-free dibenzo-21-crown-7 [PDF]

, 2017
Crown ethers and their supra­molecular derivatives are well-known chelators and scavengers for a variety of cations, most notably heavier alkali and alkaline-earth ions.
Kohl, Julia, Wiedemann, Dennis
core   +1 more source

The green Knoevenagel condensation: solvent-free condensation of benzaldehydes

, 2017
This paper presents a novel, green Knoevenagel procedure for the chemical transformation of benzaldehydes into their corresponding α,β-unsaturated acids.
J. van Schijndel, L. Canalle, Dennis Molendijk, J. Meuldijk   +3 more
semanticscholar   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Microwave-Assisted Synthesis and Evaluation of Antimicrobial Activity of 3-{3-(s-Aryl and s-Heteroaromatic)acryloyl}-2Hchromen-2-one Derivatives [PDF]

, 2010
The exploration of potential utilization of microwaves as an energy source for heterocyclic synthesis was herein investigated using condensation of 3-acetylcoumarin (1) with aromatic and heteroaromatic aldehydes to afford the corresponding aromatic ...
Ajani, Al-Soud, Anderson, Anzari, Curir, DekicÌ, Devi, Gaber, Govori, Gürsoy, Hayes, Hwu, Jayashree, Kontogiorgis, Kostova, Kotali, Lacy, Larsen, Lee, Lewis, Lisgarten, Luszcski, Lévai, Majumdar, Mashelkar, Meteeva, Montagner Souza, Mouri, Neyts, Pivonka, Ragitha, Raviraj, Roma, Russell, Satyanarayana, Saxena, Schobert, Siddiqui, Son, Srinivas, Tamilvanan, Tassies, Tosun, Tran, Venugopala, Yamamoto, Yenjai, Yun   +47 more
core   +1 more source