Stepping Further from Coupling Tools: Development of Functional Polymers via the Biginelli Reaction [PDF]
Molecules, 2022 Multicomponent reactions (MCRs) have been used to prepare polymers with appealing functions. The Biginelli reaction, one of the oldest and most famous MCRs, has sparked new scientific discoveries in polymer chemistry since 2013.
Zeyu Ma, Bo Wang, Lei Tao
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Biginelli reaction catalyzed by copper nanoparticles. [PDF]
PLoS ONE, 2012 We recently reported a novel synthesis of copper nanoparticles from copper sulphate utilizing the charge-compensatory effect of ionic liquid [bmim]BF(4) and ethylene glycol. The nanoparticles were characterized and found to be stable for one year.
Manika Dewan +4 more
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Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction [PDF]
MoleculesThe relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric ...
Marcos Díaz-Fernández +5 more
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Efficient One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones via a Three-Component Biginelli Reaction [PDF]
Molecules, 2021 Multicomponent reactions are considered to be of increasing importance as time progresses due to the economic and environmental advantages such strategies entail.
Giovanna Bosica +3 more
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Defect-rich MOF-303 as a dual acid–base heterogeneous catalyst for the one-pot Biginelli synthesis of dihydropyrimidinones [PDF]
Scientific ReportsBifunctional MOF-303 (Al) exhibits promising catalytic activity for the Biginelli reaction. However, its intrinsic microporosity may hinder reactant and product diffusion and reducing efficiency. Introducing defects is crucial for enhancing its catalytic
Nuhaa Shaheed, Ahmad Shaabani
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Current progress in asymmetric Biginelli reaction: an update [PDF]
Molecular Diversity, 2018 The Biginelli reaction, involving a three-component reaction of an aromatic aldehyde, urea and ethyl acetoacetate, has emerged as an extremely useful synthetic tool to organic chemists for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones and related heterocyclic compounds. In the past decades, the asymmetric variants of this reaction have been at the
Majid M Heravi +2 more
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Magnetic core–shell Carrageenan moss/Fe3O4: a polysaccharide-based metallic nanoparticles for synthesis of pyrimidinone derivatives via Biginelli reaction [PDF]
Chemistry Central Journal, 2018 Magnetically recoverable polysaccharide-based metallic nanoparticles Carrageenan moss/Fe3O4 (Fe3O4@CM) was tested for the synthesis of Pyrimidinone derivatives via Biginelli reaction under reflux conditions in Water. Interestingly, Fe3O4@CM prepared from
Hossein Mohammad Zaheri +4 more
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CuI as reusable catalyst for the Biginelli reaction
Catalysis Communications, 2007 Abstract An improved protocol for the Biginelli reaction using CuI as a reusable catalyst is described. The synthesis of 3,4-dihydropyrimidin-2(1H)-ones was achieved in acetonitrile, water and under solvent-free condition. After separation of product from the reaction mixture, the mother liquor (acetonitrile or water) containing the catalyst was ...
Prodeep Phukan
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Synthesis of 3,4-dihydropyrimidines and octahydroquinazolinones by SBA-15 supported schiff-base iron (III) complex as durable and reusable catalyst under ultrasound irradiation [PDF]
Scientific ReportsBiginelli-type heterocyclic compounds are particularly important due to their several chemical reactivities and various range of pharmacological activity.
Zeynab Balali +2 more
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A copper-doped ZIF-8: a high-performance catalyst for eco-friendly Ullmann and Biginelli reactions [PDF]
Scientific ReportsMetal-organic frameworks (MOFs) with high porosity have gained significant interest in organic reactions. In this study, copper-doped ZIF-8 (Cu-ZIF-8) was synthesized at room temperature, followed by oven drying at 60 °C, and subsequently employed as a ...
Zahra Doraghi +2 more
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