Results 1 to 10 of about 392 (166)

Dihydropyrimidinones Against Multiresistant Bacteria [PDF]

open access: yesFrontiers in Microbiology, 2022
The increase in bacterial resistance to antimicrobials has led to high morbidity and mortality rates, posing a major public health problem, requiring the discovery of novel antimicrobial substances.
Claudio Martin Pereira De Pereira   +2 more
exaly   +6 more sources

Solvothermal Synthesis of Multiple Dihydropyrimidinones at a Time as Inhibitors of Eg5 [PDF]

open access: yesMolecules, 2021
Solvothermal synthesis of multiple dihydropyrimidinones at a time has been developed in inexpensive and green bio-based solvent lactic acid without any additional catalysts or additives.
Xiao-Qiang Jiang   +5 more
exaly   +6 more sources

Synthesis of 4-Aryl Substituted 3,4-Dihydropyrimidinones Using Silica-chloride Under Solvent Free Conditions

open access: yesMolecules, 2007
This paper describes an improved procedure for the efficient and facile synthesis of 4-aryl substituted 3, 4-dihydropyrimidinones under mild reaction conditions with excellent yields using inexpensive silica chloride under solvent free conditions.
Manisha Sathe
exaly   +3 more sources

Recent synthetic and medicinal perspectives of dihydropyrimidinones: A review

open access: yesEuropean Journal of Medicinal Chemistry, 2017
Dihydropyrimidines are the most important heterocyclic ring systems which play an important role in the synthesis of DNA and RNA. Synthetically they were synthesized using Multi-component reactions like Biginelli reaction and Hantzschdihydropyridine.
Ravindra Rawal, Manish Kumar Gupta
exaly   +3 more sources

The role of phosphotungstic acid in enhancing the catalytic performance of UiO-66 (Zr) and its applications as an efficient solid acid catalyst for coumarins and dihydropyrimidinones synthesis

open access: yesCatalysis Communications, 2022
In recent study, we report a facile and easy technique for the synthesis phosphotungstic acid (PTA) with different weight contents (10, 25, 50 and 75 wt%) loaded on UiO-66 (Zr) as efficient and reusable catalysts for the preparation of coumarin and ...
Fares T. Alshorifi   +4 more
doaj   +1 more source

Oxidative Dehydrogenation of Dihydropyrimidinones and Dihydropyrimidines [PDF]

open access: yesOrganic Letters, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kana, Yamamoto   +2 more
openaire   +2 more sources

Biochar-Based Graphitic Carbon Nitride Adorned with Ionic Liquid Containing Acidic Polymer: A Versatile, Non-Metallic Catalyst for Acid Catalyzed Reaction

open access: yesMolecules, 2020
A novel biochar-based graphitic carbon nitride was prepared through calcination of Zinnia grandiflora petals and urea. To provide acidic and ionic-liquid functionalities on the prepared carbon, the resultant biochar-based graphitic carbon nitride was ...
Samahe Sadjadi   +2 more
doaj   +1 more source

Bis-bromine-1,4-diazabicyclo[2.2.2]octane Complex (DABCO-Br2): An Efficient and Versatile Reagent for Preparation of Dihydropyrimidinones as a New Protocol for the Biginelli Reaction [PDF]

open access: yesشیمی کاربردی روز, 2011
A simple and efficient method for the one-pot Biginelli condensation reaction of aldehydes, β-dicarbonyl compounds and urea or thiourea employing tetrameric DABCO-bromine as a novel catalyst is described.
Gholam Hossein Mahdavinia   +3 more
doaj   +1 more source

Novel Dihydropyrimidinone Derivatives as Potential P-Glycoprotein Modulators [PDF]

open access: yesACS Omega, 2022
P-glycoprotein (Pgp), an ATP binding cassette (ABC) transporter, is an ATP-dependent efflux pump responsible for cancer multidrug resistance. As part of efforts to identify human Pgp (hPgp) inhibitors, we prepared a series of novel triazole-conjugated dihydropyrimidinones using a synthetic approach that is well suited for obtaining compound libraries ...
Sabera Bijani   +8 more
openaire   +2 more sources

FeCl3∙6H2O/TMSBr-Catalyzed Rapid Synthesis of Dihydropyrimidinones and Dihydropyrimidinethiones under Microwave Irradiation

open access: yesMolecules, 2017
An efficient and practical protocol has been developed to synthesize dihydropyrimidinones and dihydropyrimidinethiones through FeCl3∙6H2O/TMSBr-catalyzed three-component cyclocondensation under microwave irradiation.
Fei Zhao   +6 more
doaj   +1 more source

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