Pyromellitic acid grafted to cross-linked LDH by dendritic units: An efficient and recyclable heterogeneous catalyst for green synthesis of 2,3-dihydro quinazoline and dihydropyrimidinones derivatives [PDF]
Heliyon, 2023 In this work, using layered double hydroxide (LDH) inorganic substrate, melamine as binding agent and dendrimer G1 and also pyromellitic acid (PMA) organic catalytic agent a heterogeneous acid catalyst was designed and prepared.
Nastaran Ghanbari, Hossein Ghafuri
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Synthesis of 5-unsubstituted dihydropyrimidinone-4-carboxylates from deep eutectic mixtures [PDF]
Beilstein Journal of Organic Chemistry, 2022 A facile one-pot synthesis of 5-unsubstituted dihydropyrimidinones from β,γ-unsaturated ketoesters in low melting ʟ-(+)-tartaric acid–N,N-dimethylurea mixtures is reported.
Sangram Gore +2 more
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Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties [PDF]
HeliyonObjective: The rise of drug-resistant bacteria, viruses, and fungi has prompted the search for new drugs without cross-resistance to current treatments.
Madiha Kanwal +3 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Dihydropyrimidinone derivatives containing piperidine moiety were synthesised in a good yield. All the compounds were confirmed by elemental analysis and spectral data.
Mashooq Ahmad Bhat +2 more
exaly +2 more sources
Molecules, 2018 Enaminones, 4-methyl-1-[4-(piperazin/morpholin-1-yl) phenyl] pent-2-en-1-one (IIa–b) were synthesized by refluxing 1-[4-(piperazin/morpholin-1-yl) phenyl] ethan-1-one (Ia–b) with dimethylformamide dimethylacetal (DMF–DMA) without any ...
Mashooq Ahmad Bhat +2 more
exaly +3 more sources
Investigation of anti-diabetic potential and molecular simulation studies of dihydropyrimidinone derivatives [PDF]
Frontiers in Endocrinology, 2022 In an attempt to find new targets for α-amylase and α-glucosidase for the treatment of type 2 diabetes mellitus, the present study aims in determining the anti-diabetic potential of synthesized dihydropyrimidinone derivatives.
Umair Ilyas +9 more
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Dihydropyrimidinone–isatin hybrids as potent inducers of cell-cycle arrest and caspase-dependent apoptosis in MV4-11 acute myeloid leukemia cells [PDF]
RSC AdvancesA novel series of 1H-1,2,3-triazole-linked dihydropyrimidinone (DHPM)–isatin hybrids was designed, synthesized and evaluated for antiproliferative activity against MV4-11 (acute myeloid leukemia), LN229 (glioblastoma) and SHSY-5Y (neuroblastoma).
Preeti +4 more
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Functionalization of magnetic TMU-17-NH2 MOF with organic ligands for stabilization of copper species as an efficient heterogeneous catalyst for the Biginelli reaction and the synthesis of pyran derivatives [PDF]
Scientific ReportsA novel magnetic nanocatalyst, Cu@M-TMU-17-NH₂-Gly-Met, was successfully prepared through a multi-step post-synthetic modification strategy. Initially, the TMU-17-NH₂ framework was functionalized with glyoxal, followed by immobilization of metformin to ...
Roghayeh Vahedian +2 more
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Magnetic polymeric ionic liquid for both catalysis application and magnetic solid phase extraction approach [PDF]
Scientific ReportsIn this project, a new heterogeneous polymeric ionic liquid catalyst based on vinylimidazole, stabilized on magnetic nanoparticles )Fe3O4@Al2O3@[PBVIm]HSO4) was prepared.
Behrooz Maleki +4 more
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Solvothermal Synthesis of Multiple Dihydropyrimidinones at a Time as Inhibitors of Eg5
Molecules, 2021 Solvothermal synthesis of multiple dihydropyrimidinones at a time has been developed in inexpensive and green bio-based solvent lactic acid without any additional catalysts or additives.
Xiao-Qiang Jiang +5 more
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