Results 31 to 40 of about 680 (195)

Multicomponent Synthesis and Evaluation of New 1,2,3-Triazole Derivatives of Dihydropyrimidinones as Acidic Corrosion Inhibitors for Steel

Molecules, 2016
An efficient one-pot synthesis of 1,2,3-triazole derivatives of dihydropyrimidinones has been developed using two multicomponent reactions. The aldehyde-1,2,3-triazoles were obtained in good yields from in situ-generated organic azides and O ...
Rodrigo González-Olvera, Viridiana Román-Rodríguez, Guillermo E. Negrón-Silva, Araceli Espinoza-Vázquez, Francisco Javier Rodríguez-Gómez, Rosa Santillan   +5 more
doaj   +1 more source

A Five-Component Biginelli-Diels-Alder Cascade Reaction

Frontiers in Chemistry, 2018
A new multi-component condensation was discovered during the reaction of a urea, β-keto ester, and formaldehyde. In the presence of catalytic indium bromide, a Biginelli dihydropyrimidinone intermediate was further converted to a five-component ...
Taber S. Maskrey, Madeline C. Frischling, Mikhaila L. Rice, Peter Wipf   +3 more
doaj   +1 more source

A green approach for the multicomponent synthesis of polyhydroquinolines and 6-unsubstituted dihydropyrimidinones using novel highly proficient acidic ionic liquid [CEMIM][MSA] as a reusable catalyst

Catalysis Communications, 2022
Carboxylic acid functionalized imidazolium based novel acidic ionic liquid [CEMIM][MSA] was synthesized using economically feasible raw materials under very mild condition.
Priyanka Patil, Suresh Kadam, Dayanand Patil, Paresh More   +3 more
doaj   +1 more source

Sono-thermal oxidation of dihydropyrimidinones

Ultrasonics Sonochemistry, 2008
Combination of ultrasound and heat has been used for the oxidation of some ethyl 3,4-dihydropyrimidin-2(1H)-one-5-carboxylates to their corresponding ethyl pyrimidin-2(1H)-one-5-carboxylates by using potassium peroxydisulfate in aqueous acetonitrile. An ultrasonic probe of 24 kHz frequency has been used for this study.
Hamid Reza, Memarian, Asadollah, Farhadi
openaire   +2 more sources

Efficient synthesis of dihydropyrimidinones via a three-component Biginelli-type reaction of urea, alkylaldehyde and arylaldehyde

Beilstein Journal of Organic Chemistry, 2013
A one-pot three-component synthesis of dihydropyrimidinones via a molecular iodine-catalyzed tandem reaction of simple readily available mono-substituted urea, alkylaldehyde, and arylaldehyde has been developed. The reaction proceeds with high chemo- and
Haijun Qu, Xuejian Li, Fan Mo, Xufeng Lin   +3 more
doaj   +1 more source

Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3

Molecules, 2010
An efficient synthesis of novel 4-(2-phenyl-1,2,3-triazol-4-yl)-3,4-dihydro-pyrimidin-2(1H)-(thio)ones from 1,3-dicarbonyl compounds, 2-phenyl-1,2,3-triazole-4-carbaldehyde and urea or thiourea under ultrasound irradiation and using samarium perchlorate ...
Ji-De Wang, Chen-Jiang Liu
doaj   +1 more source

Synthesis of dihydropyrimidinone (DHPM) derivatives through a multicomponent reaction (MCR) and their biological activity [PDF]

, 2023
The spread of incurable diseases, especially infectious diseases caused by antibiotic-resistant bacteria and certain cancers, has become a serious public health concern.
Saifudin, Azis, Rullah, Kamal, Fauzi, Ahmad   +2 more
core   +1 more source

Self-Healing Hydrogel Dressing with Solubilized Flavonoids for Whole Layer Regeneration of Diabetic Wound. [PDF]

Adv Healthc Mater
High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Zeng Q, Du S, Yuan R, Zeng Y, Li X, Wu YW, Chen K, Tao L, Tang Z, Deng X.   +9 more
europepmc   +2 more sources

Ethyl 4-(3-bromophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Acta Crystallographica Section E, 2010
In the title compound, C14H15BrN2O3, the dihydropyrimidinone ring adopts a boat conformation. In the crystal, adjacent molecules are linked through N—H...O hydrogen bonds forming an R22(8) ring motif and generating a zigzag chain extending in ...
Rajesh G. Kalkhambkar, Haldorai Yuvaraj, D. Velmurugan, S. Sundaramoorthy   +3 more
doaj   +1 more source

Efficient synthesis of the optically active dihydropyrimidinone of a potent α_1A- selective adrenoceptor antagonist

, 2002
The convergent synthesis of a potent α1A-selective adrenoceptor antagonist is described. Salient features of the synthesis include the enzymatic resolution of a racemic dihydropyrimidinone and the use of a palladium coupling reaction in the synthesis of
Michel Chartrain, Nancy Barta, Wenjie Li, Robert D Larsen, Edward G Corley, Nori Ikemoto, Louis Matty, Kozo Gbewonyo, Paul J Reider, Jeffrey S Campbell, Russell Boyd, Richard G Ball, Daniel R Sidler, Essa Hu   +13 more
core   +1 more source