Topology-Controlled Selective Fe3+ Binding in Water by δ‑Peptides with a Dihydropyrimidinone-Containing Amino Acid [PDF]
, 2020 The effect of topology on the structure, self-assembly, and selective Fe3+ binding of δ-peptides has been investigated. A series of δ-peptides with an amino acid containing dihydropyrimidinone and o-, m-, and p-aminobenzoic acids have been designed to ...
Pradip Kumar Ghorai +9 more
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Catalysis Communications, 2022 Carboxylic acid functionalized imidazolium based novel acidic ionic liquid [CEMIM][MSA] was synthesized using economically feasible raw materials under very mild condition.
Priyanka Patil +3 more
doaj +1 more source
Molecules, 2016 An efficient one-pot synthesis of 1,2,3-triazole derivatives of dihydropyrimidinones has been developed using two multicomponent reactions. The aldehyde-1,2,3-triazoles were obtained in good yields from in situ-generated organic azides and O ...
Rodrigo González-Olvera +5 more
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A Five-Component Biginelli-Diels-Alder Cascade Reaction
Frontiers in Chemistry, 2018 A new multi-component condensation was discovered during the reaction of a urea, β-keto ester, and formaldehyde. In the presence of catalytic indium bromide, a Biginelli dihydropyrimidinone intermediate was further converted to a five-component ...
Taber S. Maskrey +3 more
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Three‐Component Biginelli Cyclocondensation Reaction Using C‐Glycosylated Substrates. Preparation of a Collection of Dihydropyrimidinone Glycoconjugates and the Synthesis of C‐Glycosylated Monastrol Analogues. [PDF]
, 2002 The aldehyde-ketoester-urea cyclocondensation reaction has been revisited using C-glycosylated reagents with the aim of exploring a potential entry to a library of dihydropyrimidinone glycoconjugates.
Simona Sabbatini +7 more
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Monastrol derivatives: in silico and in vitro cytotoxicity assessments
Research in Pharmaceutical Sciences, 2020 Background and purpose: Cancer is the leading cause of death in today’s world, therefore the efforts to achieve anticancer drugs with higher potency and fewer side effects have always been conducted by researchers in the field of pharmaceutical chemistry.
Zahra Bidram +6 more
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Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold [PDF]
, 2015 Hsp90 C-terminal ligands are potential new anti-cancer drugs alternative to the more studied N-terminal inhibitors. Here we report the identification of a new dihydropyrimidinone binding the C-terminus, which is not structurally related to other well ...
Dal Piaz, F. +18 more
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Microwave-assisted synthesis of -CF3 functionalized 3,4-dihydropyrimidinone/thione/imine derivatives by using potassium phthalimide (PPI) as a green and reusable organocatalyst and their anti-microbial evaluation [PDF]
, 2023 600-617One-pot synthesis of novel -CF3 functional group containing 3,4-dihydropyrimidinone/thione/imine derivatives 8a-l, 9a-l and 10a-l has been successfully performed in high yields through the reaction of aromatic aldehydes, β-dicarbonyl compound ...
Odiya, Suresh P +2 more
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Antibacterial Studies of Dihydropyrimidinones and Pyrimidinethiones [PDF]
Journal of Bacteriology & Mycology: Open Access, 2017 Some new dihydro pyrimidinone and pyrimidinethione compounds have been synthesized and their antibacterial activities have been studied in dimethyl formamide and dimethyl sulphoxide against some Gram positive and Gram negative bacteria For this Agar well diffusion method is used It is observed that inhibition depends on solvent bacterial strain ...
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Evaluation of anticancer and antimicrobial activities of novel dihydropyrimidinone derivatives [PDF]
Dihydropyrimidinone (DHPM) can be synthesized through a simple one-pot Biginelli reaction. Off-late medicinal properties of DHPM have been discovered. In our recent work, we have shown that the florescent property can be appended to this molecule while ...
Thangamani, Suppan +4 more
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