Results 21 to 30 of about 392 (169)

5-Acetyl-4-(2,5-dimethoxyphenyl)-6-methyl-1-(prop-2-ynyl)-3,4-dihydropyrimidin-2(1H)-one

IUCrData, 2017
In the title compound, C18H20N2O4, the 3,4-dihydropyrimidin-2(1H)-one ring has a screw-boat conformation. The mean plane through this heterocycle is almost perpendicular to the prop-2-ynyl chain and to the benzene ring, with which it makes a dihedral ...
Hanane Kaoukabi, Moha Taourirte, Mohamed El Azhari, Hassan B. Lazrek, Mohamed Saadi, Lahcen El Ammari   +5 more
doaj   +1 more source

Antioxidant Compounds in the Treatment of Alzheimer’s Disease: Natural, Hybrid, and Synthetic Products

Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Alzheimer’s disease (AD) which is associated with cognitive dysfunction and memory lapse has become a health concern. Various targets and pathways have been involved in AD’s progress, such as deficit of acetylcholine (ACh), oxidative stress, inflammation, β‐amyloid (Aβ) deposits, and biometal dyshomeostasis.
Maryam Hatami, Mojtaba Mortazavi, Zahra Baseri, Batool Khani, Mehdi Rahimi, Sahar Babaei, Duygu Ağagündüz   +6 more
wiley   +1 more source

Synthesis, Biological Evaluation, 2D-QSAR, and Molecular Simulation Studies of Dihydropyrimidinone Derivatives as Alkaline Phosphatase Inhibitors [PDF]

ACS Omega, 2022
Reem Altaf, Humaira Nadeem, Muhammad Nasir Iqbal, Umair Ilyas, Zaman Ashraf, Muhammad Imran, Syed Aun Muhammad   +6 more
doaj   +2 more sources

Mechanochemistry: New Tools to Navigate the Uncharted Territory of “Impossible” Reactions

ChemSusChem, Volume 15, Issue 17, September 7, 2022., 2022
Mission impossible: Mechanosynthesis is erroneously perceived as an enabling tool for only making greener well‐known solution‐based processes. Modern mechanochemistry is, above all, an effective tool to open synthetic paths not accessible by following conventional and well‐known pathways already reported in the literature for the classical chemistry in
Federico Cuccu, Lidia De Luca, Francesco Delogu, Evelina Colacino, Niclas Solin, Rita Mocci, Andrea Porcheddu   +6 more
wiley   +1 more source

Efficient synthesis of dihydropyrimidinones via a three-component Biginelli-type reaction of urea, alkylaldehyde and arylaldehyde

Beilstein Journal of Organic Chemistry, 2013
A one-pot three-component synthesis of dihydropyrimidinones via a molecular iodine-catalyzed tandem reaction of simple readily available mono-substituted urea, alkylaldehyde, and arylaldehyde has been developed. The reaction proceeds with high chemo- and
Haijun Qu, Xuejian Li, Fan Mo, Xufeng Lin   +3 more
doaj   +1 more source

Multicomponent Synthesis and Evaluation of New 1,2,3-Triazole Derivatives of Dihydropyrimidinones as Acidic Corrosion Inhibitors for Steel

Molecules, 2016
An efficient one-pot synthesis of 1,2,3-triazole derivatives of dihydropyrimidinones has been developed using two multicomponent reactions. The aldehyde-1,2,3-triazoles were obtained in good yields from in situ-generated organic azides and O ...
Rodrigo González-Olvera, Viridiana Román-Rodríguez, Guillermo E. Negrón-Silva, Araceli Espinoza-Vázquez, Francisco Javier Rodríguez-Gómez, Rosa Santillan   +5 more
doaj   +1 more source

Sono-thermal oxidation of dihydropyrimidinones

Ultrasonics Sonochemistry, 2008
Combination of ultrasound and heat has been used for the oxidation of some ethyl 3,4-dihydropyrimidin-2(1H)-one-5-carboxylates to their corresponding ethyl pyrimidin-2(1H)-one-5-carboxylates by using potassium peroxydisulfate in aqueous acetonitrile. An ultrasonic probe of 24 kHz frequency has been used for this study.
Hamid Reza, Memarian, Asadollah, Farhadi
openaire   +2 more sources

A Five-Component Biginelli-Diels-Alder Cascade Reaction

Frontiers in Chemistry, 2018
A new multi-component condensation was discovered during the reaction of a urea, β-keto ester, and formaldehyde. In the presence of catalytic indium bromide, a Biginelli dihydropyrimidinone intermediate was further converted to a five-component ...
Taber S. Maskrey, Madeline C. Frischling, Mikhaila L. Rice, Peter Wipf   +3 more
doaj   +1 more source

A green approach for the multicomponent synthesis of polyhydroquinolines and 6-unsubstituted dihydropyrimidinones using novel highly proficient acidic ionic liquid [CEMIM][MSA] as a reusable catalyst

Catalysis Communications, 2022
Carboxylic acid functionalized imidazolium based novel acidic ionic liquid [CEMIM][MSA] was synthesized using economically feasible raw materials under very mild condition.
Priyanka Patil, Suresh Kadam, Dayanand Patil, Paresh More   +3 more
doaj   +1 more source

Ultrasound-Assisted Synthesis of Novel 4-(2-Phenyl-1,2,3-Triazol-4-yl)-3,4-Dihydropyrimidin-2(1H)-(Thio)ones Catalyzed by Sm(ClO4)3

Molecules, 2010
An efficient synthesis of novel 4-(2-phenyl-1,2,3-triazol-4-yl)-3,4-dihydro-pyrimidin-2(1H)-(thio)ones from 1,3-dicarbonyl compounds, 2-phenyl-1,2,3-triazole-4-carbaldehyde and urea or thiourea under ultrasound irradiation and using samarium perchlorate ...
Ji-De Wang, Chen-Jiang Liu
doaj   +1 more source