Results 21 to 30 of about 843 (203)

A Review on Medicinal Chemistry and Biological Activity of Dihydropyrimidinones Against HIV. [PDF]

Arch Pharm (Weinheim)
This article presents the latest advances in the development of dihydropyrimidinone (DHPM) derivatives as promising candidates against HIV. By exploring their interactions with essential viral targets and highlighting innovative compounds with potent antiviral activity, we provide an updated perspective on the opportunities for new antiretroviral ...
Leite DI, Macedo FB, Lima MMC, Brum IS, Oliveira JFM, Costa ACS, Duarte SC, Moon S, Moura SCB, Oliveira AP, Boechat N, Bastos MM.   +11 more
europepmc   +2 more sources

The role of phosphotungstic acid in enhancing the catalytic performance of UiO-66 (Zr) and its applications as an efficient solid acid catalyst for coumarins and dihydropyrimidinones synthesis

Catalysis Communications, 2022
In recent study, we report a facile and easy technique for the synthesis phosphotungstic acid (PTA) with different weight contents (10, 25, 50 and 75 wt%) loaded on UiO-66 (Zr) as efficient and reusable catalysts for the preparation of coumarin and ...
Fares T. Alshorifi, Dina E. Tobbala, Salah M. El-Bahy, Mohamed A. Nassan, Reda S. Salama   +4 more
doaj   +1 more source

Oxidative Dehydrogenation of Dihydropyrimidinones and Dihydropyrimidines [PDF]

Organic Letters, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kana, Yamamoto, Ye Grace, Chen, Frédéric G, Buono   +2 more
openaire   +2 more sources

Pivalic acid assisted Biginelli reaction for synthesis of dihydropyrimidinones and dihydrothiopyrimidinones     [PDF]

, 2021
Herein is provided an alternate, simple, multigram scale, efficient route for Biginelli reaction for synthesis of dihydropyrimidinones using urea, ethylacetatoacetate, and benzaldehyde with pivalic ...
Chodankar, Anika Arjun; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Anveka, Tushar S; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Vaz, Teotone ; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Kadam, Hari K; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Gaonkar, Saurabh Sudan; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Salgaonkar, Lalitprabha N; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Mhaldar, Shashank N; Department of Chemistry, Goa University, Taleigao Plateau, Goa 403 206, India, Gawas, Anushri Laxman; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Vernekar, Shruti Sagun; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India   +8 more
core   +2 more sources

Multigram-Scale Organic Synthesis by Resonant Acoustic Mixing: Application to the Sustainable Preparation of Active Pharmaceutical Ingredients. [PDF]

ChemSusChem
Knoevenagel condensation, Biginelli three‐component reaction and benzylic rearrangement are investigated at multi‐gram scale, by resonance acoustic mixing (RAM), to prepare biologically active molecules, also including the marketed Phenytoin (antiepileptic drug). Chem21 and DOZN 3.0 tools were used to assess the greenness of the RAM‐assisted syntheses,
Chatzigiannis CM, Scalzullo SM, Colacino E, Rivas ME.   +3 more
europepmc   +2 more sources

Novel Dihydropyrimidinone Derivatives as Potential P-Glycoprotein Modulators [PDF]

ACS Omega, 2022
P-glycoprotein (Pgp), an ATP binding cassette (ABC) transporter, is an ATP-dependent efflux pump responsible for cancer multidrug resistance. As part of efforts to identify human Pgp (hPgp) inhibitors, we prepared a series of novel triazole-conjugated dihydropyrimidinones using a synthetic approach that is well suited for obtaining compound libraries ...
Sabera Bijani, Faraz Shaikh, Sheefa Mirza, Shirley Weng In Siu, Nayan Jain, Rakesh Rawal, Nigel G. J. Richards, Anamik Shah, Ashish Radadiya   +8 more
openaire   +2 more sources

Biochar-Based Graphitic Carbon Nitride Adorned with Ionic Liquid Containing Acidic Polymer: A Versatile, Non-Metallic Catalyst for Acid Catalyzed Reaction

Molecules, 2020
A novel biochar-based graphitic carbon nitride was prepared through calcination of Zinnia grandiflora petals and urea. To provide acidic and ionic-liquid functionalities on the prepared carbon, the resultant biochar-based graphitic carbon nitride was ...
Samahe Sadjadi, Fatemeh Koohestani, Majid Heravi   +2 more
doaj   +1 more source

Stereochemistry of Dihydropyrimidinones Derivatives Synthesized by Brick Dust Catalytic Reaction [PDF]

, 2022
A number of catalytic synthetic reactions have been reported which play the important role in stereochemistry of compounds. The key to the success of this protocol was the generation of stereogenic centers in 1, 4-Dihydropyrimidinones (DHPMs) and the ...
Divya Chauhan, Surendra Kumar Nayak, Sanjeev Kumar Sahu   +2 more
core   +1 more source

Bis-bromine-1,4-diazabicyclo[2.2.2]octane Complex (DABCO-Br2): An Efficient and Versatile Reagent for Preparation of Dihydropyrimidinones as a New Protocol for the Biginelli Reaction [PDF]

شیمی کاربردی روز, 2011
A simple and efficient method for the one-pot Biginelli condensation reaction of aldehydes, β-dicarbonyl compounds and urea or thiourea employing tetrameric DABCO-bromine as a novel catalyst is described.
Gholam Hossein Mahdavinia, Mohammad Ali Bigdeli, Samaneh Karimi, Fatemeh Koti   +3 more
doaj   +1 more source

Triethylammonium acetate ionic liquid assisted one-pot synthesis of dihydropyrimidinones and evaluation of their antioxidant and antibacterial activities [PDF]

, 2017
A mild and efficient catalytic method has been developed to synthesize 3,4-dihydropyrimidinones in high yield by one-pot three component Biginelli condensation in the presence of triethylammonium acetate (TEAA) which acts as catalyst/reaction medium ...
Attri, Pankaj, Kumar, Naresh, Arora, Bharti, Choi, Eun Ha, Gupta, Anjali, Gaur, Jitender, Bhatia, Rohit   +6 more
core   +2 more sources