Results 21 to 30 of about 1,311 (206)

The role of phosphotungstic acid in enhancing the catalytic performance of UiO-66 (Zr) and its applications as an efficient solid acid catalyst for coumarins and dihydropyrimidinones synthesis

Catalysis Communications, 2022
In recent study, we report a facile and easy technique for the synthesis phosphotungstic acid (PTA) with different weight contents (10, 25, 50 and 75 wt%) loaded on UiO-66 (Zr) as efficient and reusable catalysts for the preparation of coumarin and ...
Fares T. Alshorifi, Dina E. Tobbala, Salah M. El-Bahy, Mohamed A. Nassan, Reda S. Salama   +4 more
doaj   +1 more source

Oxidative Dehydrogenation of Dihydropyrimidinones and Dihydropyrimidines [PDF]

Organic Letters, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kana, Yamamoto, Ye Grace, Chen, Frédéric G, Buono   +2 more
openaire   +2 more sources

Cytotoxic Evaluation, Molecular Docking, and 2D-QSAR Studies of Dihydropyrimidinone Derivatives as Potential Anticancer Agents. [PDF]

J Oncol, 2022
The diverse pharmacological role of dihydropyrimidinone scaffold has made it to be an interesting drug target. Because of the high incidence and mortality rate of breast cancer, there is a dire need of discovering new pharmacotherapeutic agents in managing this disease.
Altaf R, Nadeem H, Ilyas U, Iqbal J, Paracha RZ, Zafar H, Paiva-Santos AC, Sulaiman M, Raza F.   +8 more
europepmc   +2 more sources

Novel Dihydropyrimidinone Derivatives as Potential P-Glycoprotein Modulators [PDF]

ACS Omega, 2022
P-glycoprotein (Pgp), an ATP binding cassette (ABC) transporter, is an ATP-dependent efflux pump responsible for cancer multidrug resistance. As part of efforts to identify human Pgp (hPgp) inhibitors, we prepared a series of novel triazole-conjugated dihydropyrimidinones using a synthetic approach that is well suited for obtaining compound libraries ...
Sabera Bijani, Faraz Shaikh, Sheefa Mirza, Shirley Weng In Siu, Nayan Jain, Rakesh Rawal, Nigel G. J. Richards, Anamik Shah, Ashish Radadiya   +8 more
openaire   +2 more sources

Biochar-Based Graphitic Carbon Nitride Adorned with Ionic Liquid Containing Acidic Polymer: A Versatile, Non-Metallic Catalyst for Acid Catalyzed Reaction

Molecules, 2020
A novel biochar-based graphitic carbon nitride was prepared through calcination of Zinnia grandiflora petals and urea. To provide acidic and ionic-liquid functionalities on the prepared carbon, the resultant biochar-based graphitic carbon nitride was ...
Samahe Sadjadi, Fatemeh Koohestani, Majid Heravi   +2 more
doaj   +1 more source

Bis-bromine-1,4-diazabicyclo[2.2.2]octane Complex (DABCO-Br2): An Efficient and Versatile Reagent for Preparation of Dihydropyrimidinones as a New Protocol for the Biginelli Reaction [PDF]

شیمی کاربردی روز, 2011
A simple and efficient method for the one-pot Biginelli condensation reaction of aldehydes, β-dicarbonyl compounds and urea or thiourea employing tetrameric DABCO-bromine as a novel catalyst is described.
Gholam Hossein Mahdavinia, Mohammad Ali Bigdeli, Samaneh Karimi, Fatemeh Koti   +3 more
doaj   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds. [PDF]

ChemMedChem
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Martinho N, Aniceto N.
europepmc   +2 more sources

Synthesis of Quinazolin‐2,4,6‐triamine Derivatives as Non‐purine Xanthine Oxidase Inhibitors and Exploration of Their Toxicological Potential**

ChemMedChem, Volume 18, Issue 20, October 17, 2023., 2023
One quinazolin‐2,4,6‐triamine derivative was found to be a better bovine xanthine oxidase (bXO) inhibitor than allopurinol. Three quinazoline derivatives were not micronuclei inducers in a murine model. Three quinazolin‐2,4,6‐triamine derivatives acted as superoxide scavengers, and one 5,6‐dihydro‐3H‐pirimidin‐4‐one showed bXO inhibitory activity ...
Marcela A. Lopez‐Sanchez, María del Carmen Garcia‐Rodriguez, Rodrigo Aguayo‐Ortiz, Estefani Hernandez‐Cruz, Diego I. Figueroa‐Figueroa, Francisco Hernandez‐Luis   +5 more
wiley   +1 more source

Mechanochemistry: New Tools to Navigate the Uncharted Territory of “Impossible” Reactions

ChemSusChem, Volume 15, Issue 17, September 7, 2022., 2022
Mission impossible: Mechanosynthesis is erroneously perceived as an enabling tool for only making greener well‐known solution‐based processes. Modern mechanochemistry is, above all, an effective tool to open synthetic paths not accessible by following conventional and well‐known pathways already reported in the literature for the classical chemistry in
Federico Cuccu, Lidia De Luca, Francesco Delogu, Evelina Colacino, Niclas Solin, Rita Mocci, Andrea Porcheddu   +6 more
wiley   +1 more source

Chemoselective Protection and Deprotection of Aldehydes Using Solid Supported Reagent (Silica Chloride) under Solvent-Free Conditions [PDF]

, 2011
Silica chloride, a heterogeneous catalyst, has been found to be an efficient catalyst for the protection of aldehydes as acylals under solvent-free conditions, and deprotection of acylals to aldehydes in methanol as a solvent occurred. The reaction takes
Banditadatta, ., Pasha, M.A.
core   +1 more source