Results 31 to 40 of about 392 (166)

Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES

Bulletin of the Chemical Society of Ethiopia, 2017
The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by N-formyl urea to produce highly functionalized dihydropyrimidinones in fairly good yields.
A. Naderi, B. Mohtat
doaj   +1 more source

Synthesis of 2-substituted benzimidazole, coumarin, benzo[b][1,4]oxazin and dihydropyrimidinone derivatives using core-shell structured Fe3O4@SiO2-ZnCl2 nanoparticles as an effective catalyst

Results in Chemistry, 2020
In this paper, a magnetic nanocatalyst of Fe3O4@SiO2-ZnCl2 has been used which enhances the synthesis of benzimidazoles, coumarins, benzoxazines and dihydropyrimidinones. To begin with, 2-substituted benzimidazoles have been synthesized in proper to high
Saba Rahimi, Ebrahim Soleimani
doaj   +1 more source

Ultrasound-assisted one-pot synthesis of dihydropyrimid-2-one/thiones catalyzed by zirconyl chloride hexahydrate [PDF]

مجلة التربية والعلم, 2013
Different substituted dihydropyrimidinones and  dihydropyrimidin thiones were generated from the Biginelli reaction between aromatic aldehydes, 1,3-dicarbonyl and urea or thiourea under ultrasonic irradiation method.
Omar Yahya, Badie Ahmed, Imad Thanoon
doaj   +1 more source

Comparison of Catalytic Effect of Alkali and Alkaline Earth Metals Hydrogen Sulfate: As the Promoter for an Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones under Solvent-Free Conditions [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2005
Alkali and alkaline earth metals hydrogen sulfate catalyzed the one-pot three component condensation reactions of aldehydes, 1,3-dicarbonyl compounds and urea or thiourea under solvent-free conditions leading to 3,4-dihydropyrimidin-2(1H)-ones in high ...
Ahmad Shaabani, Ayoob Bazgir, Sakineh Arab Ameri, Masoumeh Sharifi Kiasaraie, Sima Samadi   +4 more
doaj  

Sulfated Zirconia-Catalyzed Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (DHPMs) Under Solventless Conditions: Competitive Multicomponent Biginelli vs. Hantzsch Reactions

Molecules, 2006
The catalytic ability of ZrO2/SO42- to promote solventless three-componentcondensation reactions of a diversity of aromatic aldehydes, urea or thoiurea and ethylacetoacetate was studied.
Guillermo Negrón-Silva, Eduardo González-Zamora, Victor H. Lara-Corona, Leticia Lomas-Romero, Deyanira Angeles-Beltrán   +4 more
doaj   +1 more source

Synthesis and Antioxidant Activity of Novel Biginelli Adducts with Phenolic Fragments

Applied Sciences
In this work, eco-friendly ceric ammonium nitrate (CAN) and ferric chloride hexahydrate catalysts in ethanol/acetonitrile systems were used to efficiently synthesize novel dihydropyrimidinone (-thione) derivatives via the Biginelli reaction. The obtained
Olga V. Snastina, Erik R. Sabitov, Viktoria A. Kuricheva, Vladimir N. Koshelev   +3 more
doaj   +1 more source

An Efficient Synthesis of 5-Alkoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones Catalyzed by KSF Montmorillonite

Molecules, 2000
A mild and efficient catalytic method for synthesis of 5-alkoxycarbonyl-4-aryl-3,4- dihydropyrimidin-2(1H)-ones using KSF montmorillonite as catalyst is described.
Ziyi Zhang, Xianten Chen, Jinchang Ding, Haixia Lin   +3 more
doaj   +1 more source

A green approach for the multicomponent synthesis of polyhydroquinolines and 6-unsubstituted dihydropyrimidinones using novel highly proficient acidic ionic liquid [CEMIM][MSA] as a reusable catalyst

Catalysis Communications, 2022
Carboxylic acid functionalized imidazolium based novel acidic ionic liquid [CEMIM][MSA] was synthesized using economically feasible raw materials under very mild condition.
Priyanka Patil, Suresh Kadam, Dayanand Patil, Paresh More   +3 more
doaj   +1 more source

Rational Design, Synthesis, and Biological Evaluation of New Substituted Dihydropyrimidinones as Antibacterial Agents and β‐Lactamase Inhibitors

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Novel 1,6‐dihydropyrimidinones act as antibacterial agents and beta‐lactamase inhibitors. Compounds 3d, 3i, and 7b demonstrated enhanced beta‐lactamase inhibition relative to the standard reference, clavulanic acid, demonstrating significant potentiation effects to restore antibiotic efficacy and combat resistant bacterial strains. ABSTRACT A series of
Ahmed M. Soliman, Heba Abdelrasheed Allam, Walaa R. Mahmoud, Bassem H. Naguib   +3 more
wiley   +1 more source

STARCH SULFURIC ACID: AN ALTERNATIVE, ECO-FRIENDLY CATALYST FOR BIGINELLI REACTION [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2013
The one-pot multicomponent synthesis of 3,4-dihydropyrimidinone derivatives using starch sulfuric acid as an environmentally friendly biopolymer-based solid acid catalyst from aldehydes, β-keto esters and urea/ thiourea without solvent is described ...
Ramin Rezaei, Sara Malek, Mohammad Reza Sheikhi, Mohammad Kazem Mohammadi   +3 more
doaj