Results 41 to 50 of about 1,953 (199)

Synthesis of novel adamantane-containing dihydropyrimidines utilizing Biginelli condensation reaction [PDF]

, 2023
Novel dihydropyrimidines incorporating an adamantane motif have been synthesized using a three-component Biginelli reaction of adamantane-containing β-keto amide N-1-adamantyl acetoacetamide as active methylene compound, thiourea, and aromatic aldehydes ...
Adeleh Moshtaghi Zonouz (14423510), Mina Abkar Aras (14423507)   +1 more
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Biginelli Reaction under Solvent‐Free Conditions [PDF]

, 2013
Biologically important 12 new important 3,4-dihydropyrimidin-2-(1H)-ones (-thiones) were synthesized with in one-pot three-component Biginelli reaction from the corresponding aromatic aldehydes (5-methyl-2-thiophenecarboxaldehyde and 2-chloro-5 ...
Gulten, Sirin, Şirin Gülten
core   +1 more source

Organocatalytic Asymmetric Biginelli-like Reaction Involving Isatin [PDF]

, 2016
The first asymmetric, Brønsted acid catalyzed Biginelli-like reaction of a ketone has been developed, employing N-substituted isatins as carbonyl substrates, and urea and alkyl acetoacetates as further components.
F. Meneghetti, Mattia Stucchi (1493920), Silvani, Alessandra, Giordano Lesma (1493932), M. Stucchi, Stucchi, Mattia, Meneghetti, Fiorella, Giulia Rainoldi (1493917), A. Sacchetti, Fiorella Meneghetti (1493926), Alessandra Silvani (1493923), G. Rainoldi, SACCHETTI, ALESSANDRO, A. Silvani, Lesma, Giordano, Rainoldi, Giulia, G. Lesma, Alessandro Sacchetti (1493929)   +17 more
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Bis-bromine-1,4-diazabicyclo[2.2.2]octane Complex (DABCO-Br2): An Efficient and Versatile Reagent for Preparation of Dihydropyrimidinones as a New Protocol for the Biginelli Reaction [PDF]

شیمی کاربردی روز, 2011
A simple and efficient method for the one-pot Biginelli condensation reaction of aldehydes, β-dicarbonyl compounds and urea or thiourea employing tetrameric DABCO-bromine as a novel catalyst is described.
Gholam Hossein Mahdavinia, Mohammad Ali Bigdeli, Samaneh Karimi, Fatemeh Koti   +3 more
doaj   +1 more source

One pot three components solvent free synthesis of 4-substituted phenyl-2-(sulfanyl/oxo) pyrimidine-5-carboxylate derivatives

Results in Chemistry, 2022
An efficient and simple procedure for synthesis of 3,4-dihydropyrimidinone or 3,4-thioxopyrimidinone maintaining eco-friendly protocol by introducing acetic acid as an organo-catalyst in presence of molecular sieves as water absorbent is disclosed.
Sourav Handique, Priyanka Sharma
doaj   +1 more source

Ethyl 6-Methyl-2-oxo-4-{4-[(1-phenyl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Molbank, 2019
The Biginelli reaction is an acid-catalyzed, three-component reaction between an aldehyde, a hydrogen methylene active compound, and urea (or its analogue) and constitutes a rapid and easy synthesis of highly functionalized heterocycles.
Itamar Luís Gonçalves, Gabriel Oliveira de Azambuja, Leonardo Davi, Guilherme Arraché Gonçalves, Luciano Porto Kagami, Gustavo Machado das Neves, João Pedro Silveira, Rômulo Faria Santos Canto, Vera Lucia Eifler-Lima   +8 more
doaj   +1 more source

Pivalic acid assisted Biginelli reaction for synthesis of dihydropyrimidinones and dihydrothiopyrimidinones     [PDF]

, 2021
Herein is provided an alternate, simple, multigram scale, efficient route for Biginelli reaction for synthesis of dihydropyrimidinones using urea, ethylacetatoacetate, and benzaldehyde with pivalic ...
Chodankar, Anika Arjun; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Anveka, Tushar S; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Vaz, Teotone ; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Kadam, Hari K; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Gaonkar, Saurabh Sudan; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Salgaonkar, Lalitprabha N; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Mhaldar, Shashank N; Department of Chemistry, Goa University, Taleigao Plateau, Goa 403 206, India, Gawas, Anushri Laxman; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India, Vernekar, Shruti Sagun; Department, of Chemistry, St. Xavier’s College, Mapusa, Goa 403 507, India   +8 more
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Synthesis of structurally diverse 3,4-dihydropyrimidin-2(1H)-ones via sequential Biginelli and Passerini reactions

Beilstein Journal of Organic Chemistry, 2017
The Biginelli reaction was combined with the Passerini reaction for the first time in a sequential multicomponent tandem reaction approach. After evaluation of all possible linker components and a suitable solvent system, highly functionalized ...
Andreas C. Boukis, Baptiste Monney, Michael A. R. Meier   +2 more
doaj   +1 more source

Biginelli reaction

, 2007
Department of Chemistry, Punjabi University, Patiala-147 002, Punjab, India E-mail: j_sandhu2002@yahoo.com Manuscript received 28 May 2007, revised 17 July 2007, accepted 18 July 2007 Recent advances In Biginelli reaction are summarized including its latest mechanism, developments In building blocks, catalysts variations, optimization/acceleration of ...
Saini, Anil, Kumar, Sanjay, Sandhu, Jagir S.   +2 more
openaire   +2 more sources

A new insight into the Biginelli reaction: the dawn of multicomponent click chemistry? [PDF]

, 2013
Looking at ‘old’ reactions from new perspectives sometimes brings new breakthroughs in current hot research areas. We therefore reinvestigated the successful multicomponent reactions (MCRs) in organic chemistry, and are pleased to find the Biginelli ...
Wei, Yen, Yang, Bin, Zhu, Chongyu, Fu, Changkui, Tao, Lei, Zhao, Yuan   +5 more
core   +1 more source