Results 11 to 20 of about 2,041,750 (198)
Anticancer Polymers via the Biginelli Reaction [PDF]
ACS Macro Letters, 2020 We developed a polymer-drug strategy to explore anticancer polymers. A series of monomers containing groups with potential anticancer activity have been facilely prepared through the Biginelli reaction. These monomers were used to produce water-soluble polymers through convenient radical copolymerization.
Yongsan Li +6 more
openaire +5 more sources
A Five-Component Biginelli-Diels-Alder Cascade Reaction [PDF]
Frontiers in Chemistry, 2018 A new multi-component condensation was discovered during the reaction of a urea, β-keto ester, and formaldehyde. In the presence of catalytic indium bromide, a Biginelli dihydropyrimidinone intermediate was further converted to a five-component ...
Taber S. Maskrey +3 more
doaj +2 more sources
Modification of Starch via the Biginelli Multicomponent Reaction [PDF]
Macromolecular Rapid Communications, 2019 AbstractAn efficient and straightforward modification of starch using renewable and commercially available aromatic aldehydes (benzaldehyde, vanillin, and p‐anisaldehyde) and urea via the Biginelli multicomponent reaction is reported in this work. First, starch acetoacetate (SAA) with a degree of substitution ranging from 1.4 to 2.5, depending on the ...
Eren Esen, Michael A. R. Meier
openaire +6 more sources
Microwave-Assisted Biginelli Reaction: An Old Reaction, a New Perspective [PDF]
Current Organic Synthesis, 2016 In this review, we tried to highlight the recent advances in the Biginelli reaction, leading to the synthesis of 3,4-dihydropyrimidin-2(1H)-ones, albeit only those conducted under microwave irradiation. The merits and drawbacks of these reactions are compared and discussed with those performed under conventional heating.
Mommahed Heravi, Majid +2 more
core +3 more sources
A mini-review on Biginelli adducts with notable pharmacological properties [PDF]
Journal of Advanced Research, 2015 Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3,4-dihydropyrimidin-2(1H)-ones/thiones (DHPMs) have emerged as prototypes for the design of compounds with a broad variety of biological activities.
Ângelo de Fátima +6 more
doaj +2 more sources
SPECIFIC “IONIC LIQUIDS” AS NEW ORGANOCATALYSTS OF BIGINELLI REACTION [PDF]
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2008 New ionic liquids bearing an imidazolium core with a carboxy group have been prepared in an attempt to design new organocatalysts of Biginelli reaction. Trends in the properties of these compounds are discussed.
Viorica Sargarovschi +2 more
doaj +1 more source
A four-component modified Biginelli reaction: A novel approach for C-2 functionalized dihydropyrimidines. [PDF]
Turk J Chem, 2021 A novel four component modified Biginelli reaction for the synthesis of C-2 functionalized dihydropyrimidines has been established. The approach uses assembly of less explored acetyl acetone with aromatic aldehyde, thiourea, and dimethyl sulphate to ...
Narkhede H, Dhake A, Balasubramaniyan V.
europepmc +2 more sources
A copper-doped ZIF-8: a high-performance catalyst for eco-friendly Ullmann and Biginelli reactions. [PDF]
Sci RepMetal-organic frameworks (MOFs) with high porosity have gained significant interest in organic reactions. In this study, copper-doped ZIF-8 (Cu-ZIF-8) was synthesized at room temperature, followed by oven drying at 60 °C, and subsequently employed as a ...
Doraghi Z, Alinezhad H, Ahmadi A.
europepmc +2 more sources
Sulfamide instead urea in Biginelli reaction: from black box to reality [PDF]
, 2023 The scope and limitation of classical Biginelli reaction expanded to principally novel substrates: sulfamide and its monosubstituted analogues. The preparative procedure was optimized.
Galyna, Grabchuk +6 more
core +2 more sources
Piperazine-grafted magnetic graphene oxide as a sustainable heterogeneous catalyst for solvent-free Biginelli reaction. [PDF]
RSC AdvMulti-component reactions (MCRs) are powerful tools for the one-pot synthesis of complex organic compounds, with the Biginelli reaction being one of the most important due to its versatility in synthesizing a wide range of dihydropyrimidine-2-ones (DHPMs)
Rezaei-Seresht E +4 more
europepmc +2 more sources