Defect-rich MOF-303 as a dual acid–base heterogeneous catalyst for the one-pot Biginelli synthesis of dihydropyrimidinones [PDF]
Scientific ReportsBifunctional MOF-303 (Al) exhibits promising catalytic activity for the Biginelli reaction. However, its intrinsic microporosity may hinder reactant and product diffusion and reducing efficiency. Introducing defects is crucial for enhancing its catalytic
Nuhaa Shaheed, Ahmad Shaabani
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Magnetic core–shell Carrageenan moss/Fe3O4: a polysaccharide-based metallic nanoparticles for synthesis of pyrimidinone derivatives via Biginelli reaction [PDF]
Chemistry Central Journal, 2018 Magnetically recoverable polysaccharide-based metallic nanoparticles Carrageenan moss/Fe3O4 (Fe3O4@CM) was tested for the synthesis of Pyrimidinone derivatives via Biginelli reaction under reflux conditions in Water. Interestingly, Fe3O4@CM prepared from
Hossein Mohammad Zaheri +4 more
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A mini-review on Biginelli adducts with notable pharmacological properties [PDF]
Journal of Advanced Research, 2015 Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3,4-dihydropyrimidin-2(1H)-ones/thiones (DHPMs) have emerged as prototypes for the design of compounds with a broad variety of biological activities.
Ângelo de Fátima +6 more
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CuI as reusable catalyst for the Biginelli reaction
Catalysis Communications, 2007 Abstract An improved protocol for the Biginelli reaction using CuI as a reusable catalyst is described. The synthesis of 3,4-dihydropyrimidin-2(1H)-ones was achieved in acetonitrile, water and under solvent-free condition. After separation of product from the reaction mixture, the mother liquor (acetonitrile or water) containing the catalyst was ...
Prodeep Phukan
exaly +2 more sources
Synthesis of 3,4-dihydropyrimidines and octahydroquinazolinones by SBA-15 supported schiff-base iron (III) complex as durable and reusable catalyst under ultrasound irradiation [PDF]
Scientific ReportsBiginelli-type heterocyclic compounds are particularly important due to their several chemical reactivities and various range of pharmacological activity.
Zeynab Balali +2 more
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A copper-doped ZIF-8: a high-performance catalyst for eco-friendly Ullmann and Biginelli reactions [PDF]
Scientific ReportsMetal-organic frameworks (MOFs) with high porosity have gained significant interest in organic reactions. In this study, copper-doped ZIF-8 (Cu-ZIF-8) was synthesized at room temperature, followed by oven drying at 60 °C, and subsequently employed as a ...
Zahra Doraghi +2 more
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SPECIFIC “IONIC LIQUIDS” AS NEW ORGANOCATALYSTS OF BIGINELLI REACTION [PDF]
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2008 New ionic liquids bearing an imidazolium core with a carboxy group have been prepared in an attempt to design new organocatalysts of Biginelli reaction. Trends in the properties of these compounds are discussed.
Viorica Sargarovschi +2 more
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O,S,Se-containing Biginelli products based on cyclic β-ketosulfone and their postfunctionalization [PDF]
Beilstein Journal of Organic ChemistryA one-pot three-component Biginelli synthesis of dihydropyrimidinones/thiones/selenones via acetic acid or solvent-free Yb(OTf)3-catalyzed tandem reaction of β-ketosulfone (dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide), an appropriate urea, and ...
Kateryna V. Dil, Vitalii A. Palchykov
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Sulfamide instead urea in Biginelli reaction: from black box to reality [PDF]
, 2023 The scope and limitation of classical Biginelli reaction expanded to principally novel substrates: sulfamide and its monosubstituted analogues. The preparative procedure was optimized.
Galyna, Grabchuk +6 more
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Concise Synthesis of Guanidine-Containing Heterocycles Using the Biginelli Reaction [PDF]
, 2016 Two general methods for the synthesis of 2-imino-5-carboxy-3,4-dihydropyrimidines were developed using the three-component Biginelli reaction. The first method utilizes pyrazole carboxamidine, a β-ketoester, and an aldehyde in an initial Biginelli ...
Larry E. Overman (1264596) +1 more
core +5 more sources