Results 21 to 30 of about 485,408 (262)

Efficient One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones via a Three-Component Biginelli Reaction

Molecules, 2021
Multicomponent reactions are considered to be of increasing importance as time progresses due to the economic and environmental advantages such strategies entail.
Giovanna Bosica, Fiona Cachia, Riccardo De Nittis, Nicole Mariotti   +3 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Solvent Free Synthesis of Chalcones and their Antibacterial Activities

E-Journal of Chemistry, 2005
The solvent free synthesis of six chalcones was carried out by grinding the piperanal and the acetophenone (unsubstituted, 4-methyl, 4-methoxy, 4-bromo, 4-nitro, 3-chloro) in the presence of solid sodium hydroxide with a mortar and pestle.
K. Rajendra K. Saini, S. Amit Choudhary, Yogesh. C. Joshi, P. Joshi   +3 more
doaj   +1 more source

Carboxymethyl cellulose as a green and biodegradable catalyst for the solvent-free synthesis of benzimidazoloquinazolinone derivatives

Journal of Saudi Chemical Society, 2019
Carboxymethyl cellulose (CMC) was used as an efficient, and environmentally friendly catalyst for the solvent-free three-component synthesis of quinazolinone derivatives by condensation of 2-aminobenzimidazole, dimedone or 1,3-cyclohexanedione, and ...
Maryam Karimi, M.R. Naimi-Jamal
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Value addition to underutilized oilseed crops through saponification of avocado and coconut oils in South-Kivu, Democratic Republic of Congo

Discover Applied Sciences
Underutilized oilseed crops contribute significantly to food security and poverty alleviation in the Democratic Republic of Congo (DRC). However, their potential remains underexploited due to limited data on their oil quality and potential applications ...
Jacques Kihye Byamungu, Dominique Aganze Mulume, Jean Mubalama Mondo, Joyce Eka Nshombo, Lola Konda, Justine Asifiwe Lwaboshi, Mikael Monga Mulunda   +6 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Solvent-free NMC electrodes for Li-ion batteries: unravelling the microstructure and formation of the PTFE nano-fibril network

Frontiers in Energy Research
The microstructure and electrochemical performance of solvent-free processed and slurry cast Li(Ni0.6Co0.2Mn0.2)O2 (NMC622) based electrodes for Li-ion batteries has been investigated.
G. A. B. Matthews, G. A. B. Matthews, S. Wheeler, S. Wheeler, J. Ramírez-González, J. Ramírez-González, P. S. Grant, P. S. Grant   +7 more
doaj   +1 more source