The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Effect of Solvent Polarity on the Photo-Induced Polymerization-Induced Self-Assembly of Poly(<i>tert</i>-butyl acrylate)-<i>block</i>-Polystyrene near Room Temperature. [PDF]
Zhou T, Song J, Guerin G.
europepmc +1 more source
5-Hydroxymethylfurfural (5-HMF) Production from Hexoses: Limits of Heterogeneous Catalysis in Hydrothermal Conditions and Potential of Concentrated Aqueous Organic Acids as Reactive Solvent System [PDF]
Rodrigo Otávio Lopes de Souza +3 more
openalex +1 more source
Changes in portlandite morphology with solvent composition: Atomistic simulations and experiment
Sandra Galmarini +3 more
semanticscholar +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Ultrafast Kerr Spectroscopy Reveals Bulk-Like Solvent Dynamics in Concentrated LiTFSI-Acetonitrile Electrolytes. [PDF]
Shah Y +4 more
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
DEGRADATION OF TRANSFORMER OIL (PCB COMPOUNDS) BY MICROWAVE RADIATION, ETHANOL SOLVENT, HYDROGEN PEROXIDE AND DIOXIDE TITANIUM FOR REDUCING ENVIRONMENTAL HAZARDS [PDF]
Reza Tajik +6 more
openalex
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source

