Results 61 to 70 of about 106,957 (303)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Research progress on degradative solvent extraction of low-rank coals

Meitan kexue jishu, 2023
The degradative solvent extraction of low rank coal is the use of solvents to extract low rank coal under mild conditions, through the dehydration and multi-stage separation of the raw coal： the extraction products with no water content, no ash content ...
Zhu GUO, Xian LI, Zhiyu LI, Zhenzhong HU, Mei ZHONG, Chunliang ZHAO, Ciliang XIA, Guangqian LUO, Shulin WANG, Hong YAO   +9 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Bases of inorganic and organic chemistry [PDF]

, 2016
Stated fundamental theoretical principles of general, inorganic and organic chemistry and analyzed the reactivity of the most important classes of inorganic and organic substances. A multivariate tasks and exercises for classroom and independent work are
Alami, D., Slavkova, M., Ved, M.
core  

Dehydration of solvent extract containing saccharides by bervaporation.

membrane, 1993
A study was carried out on the removal of water in ethanol-water mixtures containing maltose or glucose by pervaporation using polyimide hollow fiber membrane under various conditions for the purpose of saccharides crystallization. The membrane separation performance (permeation flux and separation factor) were influenced by operation conditions ...
Yumi Yoshikawa, Yasuyuki Yamamoto, Kanji Matsumoto   +2 more
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Temperature-Induced Phase Transformations in Tutton Salt K₂Cu(SO₄)₂(H₂O)₆: Thermoanalytical Studies Combined with Powder X-Ray Diffraction

Physchem
Tutton salts have received considerable attention due to their potential applications in thermochemical energy storage (TCHS) systems. This technology requires high-purity materials that exhibit reversible dehydration reactions, significant variations in
João G. de Oliveira Neto, Ronilson S. Santos, Kamila R. Abreu, Luzeli M. da Silva, Rossano Lang, Adenilson O. dos Santos   +5 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Energy-Saving Extractive Distillation Process for Isopropanol Dehydration with Propylene Glycol as Novel Extractive Solvent

Applied Sciences
The extractive distillation process using propylene glycol (IUPAC name: 1,2 propanediol) as an extractive agent for the separation of the isopropanol–water system was investigated in this work.
Marilena Nicolae, Mihaela Neagu, Diana Luciana Cursaru   +2 more
doaj   +1 more source

PROPIEDADES VOLUMÉTRICAS DE LA DL-ALANINA EN SOLUCIONES ACUOSAS DE TETRAFLUOROBORATO DE 1-BUTIL, 3-METILIMIDAZOLIO A DIFERENTES TEMPERATURAS

Química Nova, 2016
Densities of DL-alanine in aqueous ionic liquid, 1-butyl, 3-methylimidazolium tetrafluoroborate solutions were measured from 283.15 to 313.15 K. The densities measured were used to calculate apparent molar volumes (VΦ), apparent molar volume limits (VΦ0),
Manuel S. Páez, Francisco J. Páez, Francisco J. Torres   +2 more
doaj   +1 more source