Results 81 to 90 of about 546,844 (290)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Regeneration of Used Engine Lubrication Oil by Solvent Extraction. The Solvent Influence on Oil Ratio

open access: yesThe Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2013
Huge amounts of used lubricating oils from automotive sources are disposed of as a harmful waste into the environment. For this reason, means to recover and reuse these wastes need to be found.
Ancaelena Eliza STERPU   +2 more
doaj  

A review of 5-hydroxymethylfurfural production from fructose using heterogeneous catalysts

open access: yesBiomass Futures
The catalytic conversion of fructose into 5-hydroxymethylfurfural (HMF) is a crucial pathway for transforming renewable biomass into versatile platform chemicals, bridging the gap between carbohydrate resources and bio-based fuels, polymers, and fine ...
Nilofar Arabi   +4 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Active efflux systems in the solvent-tolerant bacterium Pseudomonas putida S12 [PDF]

open access: yes, 2002
The aim of the research presented in this thesis was to study the molecular mechanisms of organic solvent tolerance in Pseudomonas putida S12. This bacterium is capable of growth at saturated solvent concentrations, which are lethal to normal bacteria ...
Kieboom, J.
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Isosorbide and dimethyl carbonate: a green match

open access: yesBeilstein Journal of Organic Chemistry, 2016
In this review the reactivity of the bio-based platform compounds D-sorbitol and isosorbide with green reagents and solvent dimethyl carbonate (DMC) is reported.
Fabio Aricò, Pietro Tundo
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang   +7 more
wiley   +1 more source

Effect of dehydration on core body temperature of young Arabian Camels (Camelus dromedarius)

open access: yes, 2005
Department of Animal Production, College of Food Sciences and Agriculture, King Saud University, P.O. Box 2460, Riyadh 11455, Kingdom of Saudi ArabiaSix female Arabian camels (340 ±16.6 kg BW) were used to investigate the effect of dehydration on core ...
Al-Haidary, A.
core  

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