Results 51 to 60 of about 546,844 (290)

Iodine-catalyzed Transformation of Aryl-substituted Alcohols under Solvent-free and highly concentrated Reaction Conditions

Acta Chimica Slovenica, 2017
Iodine-catalyzed transformations of alcohols under solvent-free reaction conditions (SFRC) and under highly concentrated reaction conditions (HCRC) in the presence of various solvents were studied in order to gain insight into the behavior of the ...
Marjan Jereb, Dejan Vražič
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Sustainable Solvent Systems for Use in Tandem Carbohydrate Dehydration Hydrogenation

, 2016
Monophasic separation-friendly solvent systems were investigated for the sustainable acid-catalyzed dehydration of fructose to 5-hydroxymethylfurfural (HMF).
James A. Dumesic (1391653), Gretchen M. Gonzalez (1963474), Anthony J. Crisci (1724395), Ricardo Alamillo (1783630), Mark H. Tucker (1963471), Susannah L. Scott (1275360)   +5 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Enhanced Furfural Production in Deep Eutectic Solvents Comprising Alkali Metal Halides as Additives

Molecules, 2021
The addition of alkali metal halide salts to acidic deep eutectic solvents is here reported as an effective way of boosting xylan conversion into furfural.
Eduarda S. Morais, Mara G. Freire, Carmen S. R. Freire, Armando J. D. Silvestre   +3 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Transformation of fructose into 5-hydroxymethylfurfuraldehyde (HMF) via homogeneous Bro¨nsted acid-catalyzed dehydration under gamma irradiation

Results in Chemistry
One important renewable platform compound for fuel production and chemical industries is 5-hydroxymethylfurfural (HMF), which can be produced from the dehydration of fructose.
Nicha Prigyai, Nurulsafeelanaria Benwannamas, Yeyen Nurhamiyah, Phongphak Sataman, Somprasong Thongkham, Wiranee Sriwiang, Threeraphat Chutimasakul, Jirawat Trakulmututa, Tanagorn Sangtawesin   +8 more
doaj   +1 more source

Catalytic Dehydration of Fructose to 5-Hydroxymethylfurfural (HMF) in Low-Boiling Solvent Hexafluoroisopropanol (HFIP)

Molecules, 2018
A mixture of hexafluoroisopropanol (HFIP) and water was used as a new and unknown monophasic reaction solvent for fructose dehydration in order to produce HMF. HFIP is a low-boiling fluorous alcohol (b.p. 58 °C).
Sarah Tschirner, Eric Weingart, Linda Teevs, Ulf Prüße   +3 more
doaj   +1 more source

Conversion of N‐Acetylglucosamine to 3‐Acetamido‐5‐Acetylfuran over Al‐Exchanged Montmorillonite

ChemistryOpen, 2023
3‐Acetamido‐5‐acetylfuran (3A5AF) is a potential platform compound for the production of nitrogen‐containing pharmaceuticals and chemicals. 3A5AF can be obtained by dehydration of chitin or its monomer, N‐acetylglucosamine (NAG).
Dr. Kiyoyuki Yamazaki, Dr. Norihito Hiyoshi, Dr. Aritomo Yamaguchi   +2 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source