From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Different view of solvent effect on the synthesis methods of zeolitic imidazolate framework-8 to tuning the crystal structure and properties. [PDF]
Akhundzadeh Tezerjani A +2 more
europepmc +1 more source
The extraction of lincomycin with long-chain alcohols as solvent was studied. The experimental results indicate that the power of n-alkyl alcohols for the extraction of lincomycin depends mainly on the molarity of alcohols in solvent used.
Wu, ZC, Chen, JY, Xu, RF
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Influence of solvent effect, temperature, and pressure on the aggregation behavior of island model asphaltene: a molecular dynamics study. [PDF]
Hu C +12 more
europepmc +1 more source
Electrochemical Synthesis of Organic Polysulfides from Disulfides by Sulfur Insertion from S8 and an Unexpected Solvent Effect on the Product Distribution. [PDF]
Fährmann J, Hilt G.
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Application of the solvent effect on bioluminescent reporter bacteria as a real-time membrane toxicity assay. [PDF]
Myer PR, Turco RF, Applegate BM.
europepmc +1 more source
Non-covalent interaction, adsorption characteristics and solvent effect of procainamide anti-arrhythmias drug on silver and gold loaded silica surfaces: SERS spectroscopy, density functional theory and molecular docking investigations. [PDF]
Vetrivelan V +3 more
europepmc +1 more source

