Results 21 to 30 of about 1,724,960 (182)

Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling

open access: yesNature Communications, 2022
Tumor loss of IFN-γ signalling is a major mechanism of resistance to immune checkpoint blockers. Here the authors report that melanoma cells with knockout of IFNγR1 show constitutive JAK1/2 activation and that the JAK1/2 inhibitor ruxolitinib can ...
Hongxing Shen   +13 more
doaj   +1 more source

Case report kidney rupture: An unusual cause of abdominal pain, flank pain and hematuria in a 72-year-Old female

open access: yesJEM Reports, 2023
Background: Flank pain, abdominal pain and hematuria are common complaints in emergency medicine. Case report: We describe the case of a 72-year-old female who presented to the emergency department for worsening left lower quadrant abdominal pain and ...
Monica Diep   +4 more
doaj   +1 more source

Living roots magnify the response of soil organic carbon decomposition to temperature in temperate grassland

open access: yesGlobal Change Biology, Volume 21, Issue 3, Page 1368-1375, March 2015., 2015
Abstract Increasing atmospheric carbon dioxide (CO2) concentration is both a strong driver of primary productivity and widely believed to be the principal cause of recent increases in global temperature. Soils are the largest store of the world's terrestrial C. Consequently, many investigations have attempted to mechanistically understand how microbial
Paul W. Hill   +6 more
wiley   +1 more source

An Atypical 15q11.2 Microdeletion Not Involving SNORD116 Resulting in Prader–Willi Syndrome

open access: yesCase Reports in Genetics, 2023
Loss of expression of paternally imprinted genes in the 15q11.2-q13 chromosomal region leads to the neurodevelopmental disorder Prader–Willi Syndrome (PWS).
Molly M. Crenshaw   +6 more
doaj   +1 more source

Abstract 1122‐000096: Transradial Results in Faster Recanalization in Left Anterior Circulation Stroke and Bovine Arch

open access: yesStroke: Vascular and Interventional Neurology, 2021
Introduction: We compared technical and clinical outcomes of transradial (TRA) versus transfemoral (TFA) access for mechanical thrombectomy (MT) of acute ischemic stroke (AIS) due to large vessel occlusion (LVO) in the left anterior cerebral circulation ...
Jorge H Moreno   +6 more
doaj   +1 more source

BILLEDET SOM OPLEVELSESFÆNOMEN, SOM AFBILDNING OG SOM SELVSTÆNDIGGJORT GENSTAND

open access: yesPsyke & Logos, 2022
Temaet i dette nummer af Psyke & Logos hedder Billede og Virkelighed, og der er primært tale om en udvidet præsentation af de foredrag, der blev bragt på Psyke & Logos' åbne konference på KUA i januar, dette år. Pånogle punkter lægger dette tema sig tæt op ad temaet Narrativitet, som vi bragte for et år siden, samtidig er der imidlertid også en
openaire   +1 more source

Recurrent hyperkalemia in patients with chronic kidney disease and hepatitis C treated with direct antiviral agents

open access: yesBMC Infectious Diseases, 2019
Background Sofosbuvir is the keystone of direct antiviral agents for the chronic hepatitis C (CHC). The safety of sofosbuvir in patients with stage 4–5 chronic kidney disease (CKD) needs further observation in real world.
Taotao Yan   +14 more
doaj   +1 more source

Iris Recognition Using Hybrid Self-Organizing Map Classifier and Daugman’s Algorithm

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2023
One of the neural network algorithms that can be used in iris recognition is self-organizing map (SOM). This algorithm has a weakness in determining the initial weight of the network, which is generally carried out randomly, which can result in a ...
Amir Saleh   +3 more
doaj   +1 more source

siRNA-Mediated β-Catenin Knockdown in Human Hepatoma Cells Results in Decreased Growth and Survival

open access: yesNeoplasia: An International Journal for Oncology Research, 2007
β-Catenin, the chief oncogenic component of the canonical Wnt pathway, is known to be involved in a variety of cancers, including hepatocellular carcinoma (HCC).
Gang Zeng   +4 more
doaj   +1 more source

Burden and trend of colorectal cancer in 54 countries of Africa 2010–2019: a systematic examination for Global Burden of Disease

open access: yesBMC Gastroenterology, 2022
Background Colorectal cancer plays significant role in morbidity, mortality and economic cost in Africa. Objective To investigate the burden and trends of incidence, mortality, and disability-adjusted life-years (DALYs) of colorectal cancer in Africa ...
Atalel Fentahun Awedew   +2 more
doaj   +1 more source

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