Results 21 to 30 of about 1,724,960 (182)
Tumor loss of IFN-γ signalling is a major mechanism of resistance to immune checkpoint blockers. Here the authors report that melanoma cells with knockout of IFNγR1 show constitutive JAK1/2 activation and that the JAK1/2 inhibitor ruxolitinib can ...
Hongxing Shen +13 more
doaj +1 more source
Background: Flank pain, abdominal pain and hematuria are common complaints in emergency medicine. Case report: We describe the case of a 72-year-old female who presented to the emergency department for worsening left lower quadrant abdominal pain and ...
Monica Diep +4 more
doaj +1 more source
Abstract Increasing atmospheric carbon dioxide (CO2) concentration is both a strong driver of primary productivity and widely believed to be the principal cause of recent increases in global temperature. Soils are the largest store of the world's terrestrial C. Consequently, many investigations have attempted to mechanistically understand how microbial
Paul W. Hill +6 more
wiley +1 more source
An Atypical 15q11.2 Microdeletion Not Involving SNORD116 Resulting in Prader–Willi Syndrome
Loss of expression of paternally imprinted genes in the 15q11.2-q13 chromosomal region leads to the neurodevelopmental disorder Prader–Willi Syndrome (PWS).
Molly M. Crenshaw +6 more
doaj +1 more source
Introduction: We compared technical and clinical outcomes of transradial (TRA) versus transfemoral (TFA) access for mechanical thrombectomy (MT) of acute ischemic stroke (AIS) due to large vessel occlusion (LVO) in the left anterior cerebral circulation ...
Jorge H Moreno +6 more
doaj +1 more source
BILLEDET SOM OPLEVELSESFÆNOMEN, SOM AFBILDNING OG SOM SELVSTÆNDIGGJORT GENSTAND
Temaet i dette nummer af Psyke & Logos hedder Billede og Virkelighed, og der er primært tale om en udvidet præsentation af de foredrag, der blev bragt på Psyke & Logos' åbne konference på KUA i januar, dette år. Pånogle punkter lægger dette tema sig tæt op ad temaet Narrativitet, som vi bragte for et år siden, samtidig er der imidlertid også en
openaire +1 more source
Background Sofosbuvir is the keystone of direct antiviral agents for the chronic hepatitis C (CHC). The safety of sofosbuvir in patients with stage 4–5 chronic kidney disease (CKD) needs further observation in real world.
Taotao Yan +14 more
doaj +1 more source
Iris Recognition Using Hybrid Self-Organizing Map Classifier and Daugman’s Algorithm
One of the neural network algorithms that can be used in iris recognition is self-organizing map (SOM). This algorithm has a weakness in determining the initial weight of the network, which is generally carried out randomly, which can result in a ...
Amir Saleh +3 more
doaj +1 more source
siRNA-Mediated β-Catenin Knockdown in Human Hepatoma Cells Results in Decreased Growth and Survival
β-Catenin, the chief oncogenic component of the canonical Wnt pathway, is known to be involved in a variety of cancers, including hepatocellular carcinoma (HCC).
Gang Zeng +4 more
doaj +1 more source
Background Colorectal cancer plays significant role in morbidity, mortality and economic cost in Africa. Objective To investigate the burden and trends of incidence, mortality, and disability-adjusted life-years (DALYs) of colorectal cancer in Africa ...
Atalel Fentahun Awedew +2 more
doaj +1 more source

