Results 81 to 90 of about 938,133 (296)

Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen [PDF]

, 2002
The weakness in myasthenia gravis (MG) is mediated by autoantibodies against adult muscle acetylcholine receptors (AChR) at the neuromuscular junction; most of these antibodies also bind to fetal AChR, which is present in the thymus.
Wilcox, Nick, Stott, David, Vincent, Angela, Beeson, David, Matthews, Ian, Sims, Gary, Ledwidge, Serena   +6 more
core   +1 more source

Vaccination with human induced pluripotent stem cells creates an antigen-specific immune response against HIV-1 gp160

Frontiers in Microbiology, 2011
Induced pluripotent stem cells (iPSCs) are artificially derived from somatic cells that have been transduced with defined reprogramming factors. A previous report has indicated the possibility of using iPSCs as an immune stimulator to generate antigen ...
Shinji eYoshizaki, Mayuko eNishi, Asami eKondo, Yoshitsugu eKojima, Naoki eYamamoto, Akihide eRyo   +5 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification

, 2007
Somatic mutations of immunoglobulin genes characterize mature memory B cells, and intraclonal B-cell diversification is typically associated with expansion of B-cell clones with greater affinity for antigen (antigen drive). Evidence for a role of antigen
Bethany E. Beasley, Marc C. Levesque, Barbara K. Goodman, Beasley, Bethany E, Kelsoe, Garnett, Goodman, Barbara K, Volkheimer, Alicia D, John F. Whitesides, J. Brice Weinberg, Alicia D. Volkheimer, Joseph O. Moore, Whitesides, John F, Jon P. Gockerman, Garnett Kelsoe, Moore, Joseph O, Levesque, Marc C, Weinberg, J Brice, Gockerman, Jon P   +17 more
core   +2 more sources

Exacerbation of allergic asthma by somatic antigen of Echinococcus granulosus in allergic airway inflammation in BALB/c mice. [PDF]

Parasit Vectors, 2022
Ghabdian S, Parande Shirvan S, Maleki M, Borji H.   +3 more
europepmc   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Somatic instability of the expanded GAA triplet-repeat sequence in Friedreich ataxia progresses throughout life [PDF]

, 2007
Friedreich ataxia (FRDA) patients are homozygous for expanded GAA triplet-repeat alleles in the FXN gene. Primary neurodegeneration involving the dorsal root ganglia (DRG) results in progressive ataxia.
Ramussen, A, Monticelli, A, De Biase, I, Al-Mahdawi, S, Cocozza, S, Pook, M A, Bidichandani, S, Cardone MF, RASMUSSEN A, D'ADDABBO, PIETRO, Teti MG, POOK M, Misceo D, MONTICELLI A, ARCHIDIACONO, Nicoletta, VENTURA, MARIO, BIDICHANDANI SI, ROCCHI, Mariano, COCOZZA, SERGIO, Capozzi O, Lomiento M, DE BIASE I, AL MAHDAWI S, Roberto R, AlMahdawi S, Cocozza S   +25 more
core   +1 more source

Determination of the Infection Dynamics of Escherichia coli O157:H7 by Bacteriophage ΦV10

Foods
ΦV10 is an Escherichia coli O157:H7-specific bacteriophage that has been used to develop luminescent reporter assays for the detection of this important foodborne pathogen.
Michael F. Oats, Claudia P. Coronel-Aguilera, Bruce M. Applegate, Laszlo N. Csonka, Arun K. Bhunia, Andrew G. Gehring, George C. Paoli   +6 more
doaj   +1 more source

Effects of adult Ascaris suum and their antigens (total and trans-cuticular excretory-secretory antigen, cuticular somatic antigen) on intestinal nutrient transport in vivo. [PDF]

Parasitology, 2023
Koehler S, Springer A, Issel N, Klinger S, Wendt M, Breves G, Strube C.   +6 more
europepmc   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source