Results 101 to 110 of about 10,841,366 (345)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Milk yield and quality at udder quarter level are influenced by quarter position, pathogen, and somatic cell score

Italian Journal of Animal Science
There is a paucity of information about milk composition and quality at the quarter level from complete milking of the udder, mainly because of the difficulties of sampling procedures which imply the adoption of a vacuum system connected to four ...
Elena Visentin, Giovanni Niero, Giulio Visentin, Martino Cassandro, Massimo De Marchi, Mauro Penasa   +5 more
doaj   +1 more source

Effect of somatic cell count and mastitis pathogens on milk composition in Gyr cows

BMC Veterinary Research, 2013
BackgroundGyr cows are well adapted to tropical conditions, resistant to some tropical diseases and have satisfactory milk production. However, Gyr dairy herds have a high prevalence of subclinical mastitis, which negatively affects their milk yield and ...
Carolina Barbosa Malek dos Reis, J. R. Barreiro, Lucinéia Mestieri, M. A. F. Porcionato, M. V. dos Santos   +4 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Recognition of members of the somatic motor chain of nerve cells by means of a fundamental type of cell structure, and the distribution of such cells in certain regions of the mammalian brain [PDF]

, 1913
Edward F. Malone
openalex   +1 more source

Interspecies somatic cell nuclear transfer: advancements and problems.

Cellular Reprogramming, 2013
Embryologists working with livestock species were the pioneers in the field of reprogramming by somatic cell nuclear transfer (SCNT). Without the "Dolly experiment," the field of cellular reprogramming would have been slow and induced plutipotent cells ...
I. Lagutina, H. Fulka, G. Lazzari, C. Galli   +3 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

The Phenotypical Correlations between Somatic Cell Count and Principals Characters of Cow Milk Production for Falticeni Area

Scientific Papers Animal Science and Biotechnologies, 2023
Researches were making on cow milk samples from three Falticeni area loclities. Studied characters were mill production, fat percent, protein percent, and somatic cell count.
Mihaela Ivancia, Constantin Pascal, Dorel Dronca, Razvan Alexandru Popa   +3 more
doaj  

Somatic cell parasitism and the evolution of somatic tissue compatibility. [PDF]

Proceedings of the National Academy of Sciences, 1982
Selection pressures proposed to account for the convergent evolution of self/not-self recognition systems in lower organisms include defense against microbial parasites and somatic cell variants. Direct support for the existence of somatic cell parasites in natural populations has been lacking. I here report the occurrence of a somatic cell parasite in
openaire   +2 more sources

JAK-STAT3 and somatic cell reprogramming

JAK-STAT, 2013
Reprogramming somatic cells to pluripotency, especially by the induced pluripotent stem cell (iPSC) technology, has become widely used today to generate various types of stem cells for research and for regenerative medicine.
Yong Tang, X. Tian
semanticscholar   +1 more source