Results 191 to 200 of about 10,841,366 (345)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Differentiation success of reprogrammed cells is heterogeneous in vivo and modulated by somatic cell identity memory. [PDF]

Stem Cell Reports
Zikmund T, Fiorentino J, Penfold C, Stock M, Shpudeiko P, Agarwal G, Langfeld L, Petrova K, Peshkin L, Hamperl S, Scialdone A, Hoermanseder E.   +11 more
europepmc   +1 more source

Expression of Malignancy in Somatic Cell Hybrids [PDF]

, 1970
G Barski
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

A chromatin-focused CRISPR screen identifies USP22 as a barrier to somatic cell reprogramming. [PDF]

Commun Biol
Gürhan G, Sevinç K, Aztekin C, Gayretli M, Yılmaz A, Yıldız AB, Ervatan EN, Morova T, Datlı E, Coleman OD, Kawamura A, Lack NA, Syed H, Önder T.   +13 more
europepmc   +1 more source

Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer

Cell, 2013
Masahito Tachibana, P. Amato, M. Sparman, Nuria Marti Gutierrez, Rebecca Tippner-Hedges, Hong Ma, Eunju Kang, A. Fulati, Hyo-Sang Lee, Hathaitip Sritanaudomchai, K. Masterson, Janine M. Larson, D. Eaton, Karen Sadler-Fredd, D. Battaglia, David M. Lee, D. Wu, Jeffrey Jensen, P. Patton, S. Gokhale, R. Stouffer, D. Wolf, S. Mitalipov   +22 more
semanticscholar   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

The Complexities of Interspecies Somatic Cell Nuclear Transfer: From Biological and Molecular Insights to Future Perspectives. [PDF]

Int J Mol Sci
Pankammoon P, Salinas MBS, Thitaram C, Sathanawongs A.   +3 more
europepmc   +1 more source

Deciphering the decisive factors driving fate bifurcations in somatic cell reprogramming. [PDF]

Mol Ther Nucleic Acids, 2023
Long C, Li H, Liang P, Chao L, Hong Y, Zhang J, Xi Q, Zuo Y.   +7 more
europepmc   +1 more source

Epigenetic variation of cultured somatic cells: evidence for gradual changes in the requirement for factors promoting cell division.

, 1977
Frederick Meins, Andrew N. Binns
openalex   +1 more source