Results 171 to 180 of about 5,368,005 (298)

Evidence of somatic cell reprogramming toward embryogenic competence revealed through morphoanatomical and biochemical transitions in Piper aduncum L. [PDF]

Protoplasma
de Souza NB, Meira RO, Scherwinski-Pereira JE.   +2 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Beware of your "oocyte specific" Cre line: somatic cell Cre expression in several Zp3-Cre lines and the Gdf9-iCre transgenic line†. [PDF]

Biol Reprod
Stein P, Emori C, Padilla-Banks E, Radonova L, Gruzdev A, Ikawa M, Williams CJ.   +6 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Differences in Peripheral Blood Gene Expression of Xinjiang Brown Cattle with Varying Somatic Cell Counts. [PDF]

Biology (Basel)
Yan M, Wang D, Ma S, Wang J, Xu L, Zhang M, Huang X.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Longitudinal studies of intramammary infection in suckler ewes [PDF]

Four longitudinal studies were conducted. The first study investigated the longitudinal pattern of udder half somatic cell count (HSCC) and intramammary infection (IMI) in 48 UK suckler ewes over the first 10 weeks of lactation.
Huntley, Selene J.
core  

Development, propagation and characterization of human somatic cell-derived bronchial organoids as model system for airway diseases - A practical guide. [PDF]

Front Allergy
Kühl L, Carvalho A, Löwer N, Miethe S, Pauck K, Roth K, von Daacke N, Graichen P, Müßig E, Huy E, Mende A, Block A, Bachl M, Pflugmacher JH, Dechert P, Potaczek DP, Sadeghi Shermeh A, Garn H.   +17 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

MiTo: tracing the phenotypic evolution of somatic cell lineages via mitochondrial single-cell multi-omics. [PDF]

Nat Commun
Cossa A, Dalmasso A, Campani G, Bugani E, Caprioli C, Bulla N, Tirelli A, Zhan Y, Pelicci PG.   +8 more
europepmc   +1 more source