Results 161 to 170 of about 267,878 (327)

Telomere Elongation and Naive Pluripotent Stem Cells Achieved from Telomerase Haplo-Insufficient Cells by Somatic Cell Nuclear Transfer

Cell Reports, 2014
Summary: Haplo-insufficiency of telomerase genes in humans leads to telomere syndromes such as dyskeratosis congenital and idiopathic pulmonary fibrosis.
Li-Ying Sung, Wei-Fang Chang, Qian Zhang, Chia-Chia Liu, Jun-Yang Liou, Chia-Chun Chang, Huan Ou-Yang, Renpeng Guo, Haifeng Fu, Winston T.K. Cheng, Shih-Torng Ding, Chuan-Mu Chen, Maja Okuka, David L. Keefe, Y. Eugene Chen, Lin Liu, Jie Xu   +16 more
doaj  

Development of Somatic Cell Nuclear Transferred Bovine Embryos in Protein Free Synthetic Oviduct Fluid Medium

, 2001
Kazuho Shiga, Tatsuo Fujita, Kouichi OOTAKE, Katsunori Kimoto   +3 more
openalex   +2 more sources

Role of chromosome stability and telomere length in the production of viable cell lines for somatic cell nuclear transfer [PDF]

, 2006
Gabriela F. Mastromonaco, Steve D. Perrault, Dean H. Betts, W.A. King   +3 more
openalex   +1 more source

3D In Vitro Glioma‐Neuron‐Astrocyte Biomimetic Composites Recapitulate Key Molecular Mechanisms Linked to Glioblastoma Multiforme Pathophysiology

Advanced Functional Materials, EarlyView.
Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier, Esra Türker, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Panthipa Suwannakot, Benedikt Gantert, Abhinav Singh, Vanessa Moessler, Annemarie Sodmann, Nicoletta Murenu, Joachim Schenk, Natascha Schaefer, Torsten Blunk, Aldo R. Boccaccini, Tessa C. Lühmann, Jörg Tessmar, Jeremy M. Crook, Eva Tomaskovic‐Crook, Paul D. Dalton, Gregor Lang, Robert Blum, Reiner Strick, Silvia Budday, Katrin G. Heinze, Carmen Villmann   +26 more
wiley   +1 more source

Defective chromatin architectures in embryonic stem cells derived from somatic cell nuclear transfer impair their differentiation potentials. [PDF]

Cell Death Dis, 2021
Wu DY, Li X, Sun QR, Dou CL, Xu T, He H, Luo H, Fu H, Bu GW, Luo B, Zhang X, Ma BG, Peng C, Miao YL.   +13 more
europepmc   +1 more source

Wave-LSTM: Multi-scale analysis of somatic whole genome copy number profiles [PDF]

arXiv
Changes in the number of copies of certain parts of the genome, known as copy number alterations (CNAs), due to somatic mutation processes are a hallmark of many cancers. This genomic complexity is known to be associated with poorer outcomes for patients but describing its contribution in detail has been difficult.
arxiv  

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

Advanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang, Xin Zhang, Denghui Xie, Chunying Chen, Zhifeng Huang, Zhong Alan Li   +5 more
wiley   +1 more source

Stem cell therapies and benefaction of somatic cell nuclear transfer cloning in COVID-19 era. [PDF]

Stem Cell Res Ther, 2021
Singh B, Mal G, Verma V, Tiwari R, Khan MI, Mohapatra RK, Mitra S, Alyami SA, Emran TB, Dhama K, Moni MA.   +10 more
europepmc   +1 more source

Non‐Enzymatic Destruction of the Extracellular Matrix for Activatable Orthotopic Tumor Treatment and Enhanced Drug Penetration

Advanced Functional Materials, EarlyView.
Supramolecular biomimetic nanoaggregates (HFCu NAs), constructed with fluorinated histidine and copper ions via metal coordination and aromatic packing, exhibit enhanced reactive oxygen species （ROS）generation at tumor sites, which results in stepwise collapse of the extracellular matrix (ECM), affording tumor microenvironment responsive “turn‐on” 19F ...
Hui Wang, Ruxin Feng, Yan Wang, Qian Ma, Di Yuan, Xi Yang, Suying Xu, Tony D. James, Leyu Wang   +8 more
wiley   +1 more source

Correction: Defective chromatin architectures in embryonic stem cells derived from somatic cell nuclear transfer impair their differentiation potentials. [PDF]

Cell Death Dis, 2021
Wu DY, Li X, Sun QR, Dou CL, Xu T, He H, Luo H, Fu H, Bu GW, Luo B, Zhang X, Ma BG, Peng C, Miao YL.   +13 more
europepmc   +1 more source