Results 61 to 70 of about 387,549 (301)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Frontiers in Plant Science, 2022 Protein fluorescence reporting systems are of crucial importance to in-depth life science research, providing systematic labeling tools for visualization of microscopic biological activities in vivo and revolutionizing basic research. Cotton somatic cell
Gai-Yuan Hu +15 more
doaj +1 more source
Embryo donation parents' attitudes towards donors : comparison with adoption [PDF]
, 2008 BACKGROUND: Embryo donation produces a family structure where neither rearing parent is genetically related to the child, as in adoption. It is not known how embryo donation parents view the donors compared with how adoptive parents view the birth ...
MacCallum, Fiona
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Micropropagation of lettuce americana via somatic embryogenesis [PDF]
Ciência Rural: This research evaluated the effect of light and the auxin naphthaleneacetic acid (NAA) on the induction of somatic embryogenesis, and of activated carbon (CA) and polyethylene glycol (PEG) on the maturation of somatic embryos of Lactuca sativa.
Luciana Coelho de Moura +4 more
doaj +2 more sources
, 2014 Extracellular proteins and glycoproteins secreted by ammonium- or auxin-induced somatic embryogenic cultures of pumpkin were analyzed. Despite an overall similarity in developmental characteristics between these embryogenic cultures, distinct expression ...
D. Leljak-Levanić +3 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Prospects for transgenesis in the chick [PDF]
, 2004 Research to develop a useful method for genetic modification of the chick has been on-going since the first demonstrations in the mouse in the 1980s that genetic modification is an invaluable tool for the study of gene function. Manipulation of the chick
Sang, Helen
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A relação do desenvolvimento de embriões somáticos iniciais de Araucaria angustifolia (Bert.) O. Kuntze com os conteúdos endógenos de carboidratos [PDF]
, 2013 TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Curso de Agronomia.A Araucaria angustifolia é uma espécie nativa do Sul do Brasil que hoje se encontra na lista das espécies ameaçadas de extinção devido à degradação ...
Pereira, Maria Luiza Tomazi
core