Results 71 to 80 of about 46,198 (262)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Direct somatic embryogenesis induction in Aspilia Africana (Pers.) C. D. Adams, and assessment of genetic homogeneity and physiology of regenerants

Scientific Reports
Aspilia africana (Pers.) C. D. Adams is a valuable medicinal plant, and the expanding therapeutic use of the plant due to explosion of human population is causing depletion of its wild population, thus requiring propagation.
Roggers Gang, Sungyu Yang, Kenneth Happy, Joyce Mudondo, Ariranur Haniffadli, Denis Okello, Yeongjun Ban, Youngmin Kang   +7 more
doaj   +1 more source

Cloning of the Coffea canephora SERK1 promoter and its molecular analysis during the cell-to-embryo transition

Electronic Journal of Biotechnology, 2018
Background: Somatic embryogenesis receptor-like kinase 1 (SERK1) is a cell membrane receptor active in different plant tissues and involved in cell differentiation activities including somatic embryogenesis.
Doribet Jiménez-Guillen, Daniel Pérez-Pascual, Ramón Souza-Perera, Gregorio Godoy-Hernández, José Juan Zúñiga-Aguilar   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Somatic embryogenesis and plant regeneration in Wedelia calendulacea Less. an endangered medicinal plant

Brazilian Archives of Biology and Technology, 2014
In this work, plant regeneration via somatic embryogenesis was achieved from leaf and internode derived callus of Wedelia calendulacea, an endangered medicinal plant.
Shamima Akhtar Sharmin, Md. Jahangir Alam, Md. Mominul Islam Sheikh, Kanak Kanti Sarker, Muhammad Khalekuzzaman, Md. Anwarul Haque, Mohammad Firoz Alam, Iftekhar Alam   +7 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

In vitro propagation of Tilia platyphyllos by axillary shoot proliferation and somatic embryogenesis

Journal of Forest Science, 2003
In vitro propagation of Tilia platyphyllos Scop. has been achieved by axillary shoot proliferation and somatic embryo-genesis. The influence of tree age, explant source, genotype, and phytohormones on micropropagation of juvenile and mature trees of ...
V. Chalupa
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Callus sieving is effective in improving synchronization and frequency of somatic embryogenesis in Citrus sinensis

Biologia Plantarum, 2011
Somatic embryogenesis has been obtained in many citrus cultivars. However, culture synchronization is yet to be achieved and in the present work we evaluate the effect of desiccation, cold and size of cell clusters on embryo production efficiency from ...
J. M. M. Souza, M. L. Tomaz, S. C. C. Arruda, C. G. B. Demétrio, W. N. Venables, A. P. Martinelli   +5 more
doaj   +1 more source