Results 81 to 90 of about 108,547 (303)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Induction of somatic embryos in cultures of Asparagus racemosus Willd: an endangered medicinally important plant

Bulletin of the National Research Centre, 2019
Background Somatic embryogenesis is one of the most popular in vitro regeneration methods for mass micropropagation. In the present study, somatic embryogenesis via zygotic embryos was studied in Asparagus racemosus Willd.
Juhi Chaudhary, Prem Kumar Dantu
doaj   +1 more source

Welfare in horse breeding [PDF]

, 2015
Welfare problems related to the way horses are bred, whether by coitus or by the application of artificial reproduction techniques (ARTs), have been given no discrete consideration within the academic literature. This paper reviews the existing knowledge
ALLEN, ANGULO, ASHLEY, BETTLEY, BUSSIÉRES, CAMPBELL, CAMPBELL, CAMPBELL, CARNEVALE, CARNEVALE, CARNEVALE, CHASTANT-MAILLARD, CHENOWETH, COOK, DALLA COSTA, DONDORP, EFSA, EFSA, EVERTS, FARIN, FARIN, FAWC, FAWC, FEI, GALLI, GALLI, GLEERUP, HARTMAN, HINRICHS, HINRICHS, HINRICHS, HOUDEBINE, JIRKOF, JOHNSON, KIM, LAGUTINA, MARI, MCDONNELL, MCDONNELL, MCEVOY, MCKINNON, MEYERS-BROWN, MILLS, PADER, PEETERS, PETYIM, RENARD, ROBERTSON, SHARP, SMITH, VAN LOON, WIKLAND, WORLD HORSE WELFARE, YOUNG   +53 more
core   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. [PDF]

, 2019
In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri ...
Aslanyan, Marianna, Chen, Di, Clark, Amander, Faith, Jared, Fu, Jianping, Hou, Lei, Kellis, Manolis, Kim, Rachel, Liu, Wanlu, Sun, Na, Tao, Yu, Zheng, Yi   +11 more
core  

The 2HA line of Medicago truncatula has characteristics of an epigenetic mutant that is weakly ethylene insensitive [PDF]

, 2016
BACKGROUND The Medicago truncatula 2HA seed line is highly embryogenic while the parental line Jemalong rarely produces embryos. The 2HA line was developed from one of the rare Jemalong regenerates and this method for obtaining a highly regenerable ...
Carroll, Bernard J, Goffard, Nicolas, Kurdyukov, Sergey, Mathesius, Ulrike, Nolan, Kim E, Rose, Ray J, Sheahan, Michael B   +6 more
core   +1 more source

Cryopreservation of Arachis pintoi (leguminosae) somatic embryos.

Cryo letters, 2013
Fil: Engelmann, Florent. Centre National de la Recherche Scientifique. Institut de Recherche Pour Le Developpement; Francia.
Rey, H.Y., Faloci, M., Medina, R., Dolce, N., /Engelmann, Florent, Mroginski, L.   +5 more
openaire   +4 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

The consequences of nuclear transfer for mammalian foetal development and offspring survival : a mitochondrial DNA perspective [PDF]

, 2004
Review of the articleThe introduction of nuclear transfer (NT) and other technologies that involve embryo reconstruction require us to reinvestigate patterns of mitochondrial DNA (mtDNA) transmission, transcription and replication.
Anderson, Barrientos, Barrientos, Barritt, Barritt, Birky, Birky, Blok, Boiani, Bortvin, Boulet, Brenner, Campbell, Cibelli, Clark, Clayton, Cohen, Cormier, Cummins, Davis, Do, Dunbar, Evans, Fisher, Gaertig, Gahan, Giles, Goto, Gyllensten, Hauswirth, Hayakawa, Hiendleder, Hoeh, Holt, Howell, Hsieh, Huo, Inoue, Jansen, Jenuth, Kaneda, Kaukonen, King, King, Laipis, Larsson, Larsson, Lazzari, Magnusson, Maher, Mandel, Marchington, Michaels, Moraes, Moyes, Pik  , Poulton, Poulton, Reik, Reynier, Saada, Schon, Schutz, Schwartz, Shi, Shitara, Shoffner, Smith, St. John, Steinborn, Steinborn, Sutovsky, Takeda, Takeda, Torroni, Van Blerkom, Van Blerkom, Van Goethem, Wakayama, Wallace, Zhang   +80 more
core   +1 more source

Elinvar Materials: Recent Progress and Challenges

Advanced Engineering Materials, EarlyView.
Elinvar materials, exhibiting temperature‐invariant elastic modulus, are critical for precision instruments and emerging technologies. This article reviews recent progress in the field, with a focus on the anomalous thermoelastic behavior observed in key material systems.
Wenjie Li, Yang Ren
wiley   +1 more source