Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. [PDF]
A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs) from pluripotent cells was ...
Chen, Di +13 more
core +2 more sources
Somatic mutation load of estrogen receptor-positive breast tumors predicts overall survival: an analysis of genome sequence data. [PDF]
Breast cancer is one of the most commonly diagnosed cancers in women. While there are several effective therapies for breast cancer and important single gene prognostic/predictive markers, more than 40,000 women die from this disease every year.
Bainbridge, Matthew N +3 more
core +1 more source
On the somatic marker hypothesis
The somatic marker hypothesis is the hypothesis of the neural mechanism which is spontaneously triggered in the process of decision making. It is about bodily changes that accompany certain ideas we relate to the prospects of our choices. The somatic marker is the feeling of these changes occurring before the decision is made.
openaire +3 more sources
Learning On The IGT Follows Emergence Of Knowledge But Not Differential Somatic Activity
The importance of unconscious autonomic activity versus knowledge in influencing behaviour on the Iowa Gambling Task (IGT) has been the subject of debate. The tasks developers, Bechara and colleagues, have claimed that behaviour on the IGT is influenced
Gordon eFernie, Richard J Tunney
doaj +1 more source
Studying the mechanisms of the Somatic Marker Hypothesis in Spiking Neural Networks (SNN)
In this paper, a mechanism of emotional bias in decision making is studied using Spiking Neural Networks to simulate the associative and recurrent networks involved. The results obtained are along the lines of those proposed by A.
Alejandro JIMÉNEZ-RODRÍGUEZ +2 more
doaj +1 more source
Marker-free transgenic plants through genetically programmed auto-excision [PDF]
We present here a vector system to obtain homozygous marker-free transgenic plants without the need of extra handling and within the same time frame as compared to transformation methods in which the marker is not removed.
Verweire, Dimitri +4 more
core +2 more sources
Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]
Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael +2 more
core +1 more source
Background The somatic cell score (SCS) is implemented in routine sire evaluations in many countries as an indicator trait for udder health. Somatic cell score is highly correlated with clinical mastitis, and in the German Holstein population ...
Reinsch Norbert +4 more
doaj +1 more source
Om religiøse følelser og deres teologiske værd
On Religious Emotions and Their Theological Value: How to Understand the Positive Significance of Christian Affections for Doctrine and Practice? The purpose of this article is to give a constructive proposal of how to understand the role of Christian ...
John Daniel L. Andersen
doaj +1 more source
Retinoic acid metabolic genes, meiosis, and gonadal sex differentiation in zebrafish. [PDF]
To help understand the elusive mechanisms of zebrafish sex determination, we studied the genetic machinery regulating production and breakdown of retinoic acid (RA) during the onset of meiosis in gonadogenesis.
Adriana Rodríguez-Marí +5 more
doaj +1 more source

