Results 71 to 80 of about 200,238 (297)

HNSC samples somatic mutation data

, 2014
TCGA HNSC samples somatic mutation data in BED format.
Endre Sebestyén (403853)
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

PRAD samples somatic mutation data

, 2014
TCGA PRAD samples somatic mutation data in BED format.
Endre Sebestyén (403853)
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

KIRC samples somatic mutation data

, 2014
TCGA KIRC samples somatic mutation data in BED format.
Endre Sebestyén (403853)
core   +1 more source

A simple consensus approach improves somatic mutation prediction accuracy [PDF]

, 2013
Differentiating true somatic mutations from artifacts in massively parallel sequencing data is an immense challenge. To develop methods for optimal somatic mutation detection and to identify factors influencing somatic mutation prediction accuracy, we ...
Campbell, IG, Rowley, SM, Georgina L Ryland, Ma, T, Doyle, Maria, David Choong, Goode, David, Sally M Hunter, Choong, D, Ryland, GL, David L Goode, Simone M Rowley, Tao Ma, Choong, David, Campbell, Ian, Ryland, Georgina L, Ian G Campbell, Hunter, SM, Ma, Tao, Maria A Doyle, Rowley, Simone, Goode, DL, Doyle, MA, Hunter, Sally   +23 more
core   +1 more source

Somatic SF3B1 hotspot mutation in prolactinomas [PDF]

, 2020
The genetic basis and corresponding clinical relevance of prolactinomas remain poorly understood. Here, we perform whole genome sequencing (WGS) on 21 patients with prolactinomas to detect somatic mutations and then validate the mutations with digital ...
Wang, Hongyun, Zhang, Qi, Li, Guilin, Qu, Yanming, Li, Chuzhong, Li, Mingxuan, Ling, Shiying, Gong, Lei, Shen, Yutao, Zhang, Yazhuo, Jiang, Tao, Zhuang, Zhengping, Zhu, Haibo, Xie, Weiyan, Zhang, Hongwei, Guo, Jing, Zhang, Mingshan, Wang, Junmei, Zhou, Jianyu, Rosenblum, Jared S, Zhao, Sida, Cheng, Sen, Wang, Fei, Ma, Jun, Miao, Yazhou   +24 more
core   +1 more source

NetNorM: Capturing cancer-relevant information in somatic exome mutation data with gene networks for cancer stratification and prognosis. [PDF]

PLoS Computational Biology, 2017
Genome-wide somatic mutation profiles of tumours can now be assessed efficiently and promise to move precision medicine forward. Statistical analysis of mutation profiles is however challenging due to the low frequency of most mutations, the varying ...
Marine Le Morvan, Andrei Zinovyev, Jean-Philippe Vert   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

LUAD samples somatic mutation data

, 2014
TCGA LUAD samples somatic mutation data in BED format.
Endre Sebestyén (403853)
core   +1 more source