Results 241 to 250 of about 1,861,621 (385)

Real-World Outcomes of Adjuvant Therapy in Stage III Melanoma and the Impact of Somatic Mutations. [PDF]

Cancer Med
Effiom D, Aprati T, Karneris A, Lawless A, Sharova T, Johnson R, Menzies A, Long G, Park B, Jung S, Johnson D, Liu D, Bai X, Flaherty K, Sullivan R, Boland GM, Cohen S.   +16 more
europepmc   +1 more source

Limited evidence that cancer susceptibility regions are preferential targets for somatic mutation

, 2015
Mitchell J. Machiela, Brian M. Ho, Victoria A. Fisher, Xing Hua, Stephen J. Chanock   +4 more
openalex   +1 more source

Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples [PDF]

, 2016
Ashraf Dallol, Abdelbaset Buhmeida, Mahmoud S. Al-Ahwal, Jaudah Al‐Maghrabi, Osama S. Bajouh, Shadi Alkhayyat, Rania Alam, Atlal Abusanad, Rola Turki, Aisha Elaimi, Hani A. Alhadrami, Mohammed Abuzenadah, Huda Banni, Mohammed Al‐Qahtani, Adel Abuzenadah   +14 more
openalex   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

SomaMutDB 2.0: A comprehensive database for exploring somatic mutations and their functional impact in normal human tissues. [PDF]

Nucleic Acids Res
Shea A, Sun S, Kennedy J, Zhang L, Vijg J, Dong X.   +5 more
europepmc   +1 more source

Somatic Mutations Drive Distinct Imaging Phenotypes in Lung Cancer.

Cancer Research, 2017
E. Rios Velazquez, C. Parmar, Y. Liu, T. Coroller, G. Cruz, O. Stringfield, Z. Ye, M. Makrigiorgos, F. Fennessy, R. Mak, R. Gillies, John Quackenbush, H. Aerts   +12 more
semanticscholar   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Sex and smoking bias in the selection of somatic mutations in human bladder. [PDF]

Nature
Calvet F, Blanco Martinez-Illescas R, Muiños F, Tretiakova M, Latorre-Esteves ES, Fredrickson J, Andrianova M, Pellegrini S, Huber AR, Ramis-Zaldivar JE, An SC, Thieme E, Kohrn BF, Grau ML, Gonzalez-Perez A, Lopez-Bigas N, Risques RA.   +16 more
europepmc   +1 more source

<b>Unilateral Primary Aldosteronism Lacking</b><b><i> KCNJ5</i></b><b> Somatic Mutations is Associated with an Elevated Risk of New-Onset Diabetes Mellitus</b> [PDF]

Chieh‐Kai Chan, Wei‐Shiung Yang, Yen‐Hung Lin, Vin‐Cent Wu, Shih‐Chieh Chueh   +4 more
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source