Results 271 to 280 of about 199,006 (315)

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Correction to 'SomaMutDB: a database of somatic mutations in normal human tissues'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Somatic Mutations in Surgically Treated Colorectal Liver Metastases: An Overview. [PDF]

Cells
Wang J, Botvinov J, Bhatt AJ, Beyer K, Kreis ME, Adam M, Alseidi A, Margonis GA.   +7 more
europepmc   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

Advanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare, Kshama Kundu, Papiya Dey, Krupa Thankam Philip, Nitish Chauhan, Muskan Sharma, Sankarsingh Kesharsingh Rajput, Birija Sankar Patro   +7 more
wiley   +1 more source

Pan-cancer discovery of somatic mutations from RNA sequencing data. [PDF]

Commun Biol
Tang G, Liu X, Cho M, Li Y, Tran DH, Wang X.   +5 more
europepmc   +1 more source

Genomic profiling of colorectal cancer in large-scale Chinese patients: amplification and somatic mutations in ERBB2. [PDF]

Oncol Res
Liu Y, Bischof E, Chen Z, Zhou J, Zhang B, Zhang D, Gao Y, Quan M.   +7 more
europepmc   +1 more source

Genomic patterns of somatic mutations provide new prognostic, therapeutic, and biological insights in cancer. [PDF]

Cell Genom
Tseitline D, Cohen Y, Adar S.
europepmc   +1 more source

ERCC2 mutations alter the genomic distribution pattern of somatic mutations and are independently prognostic in bladder cancer. [PDF]

Cell Genom
Barbour JA, Ou T, Yang H, Fang H, Yue NC, Zhu X, Wong-Brown MW, Wong YT, Bowden NA, Wu S, Wong JWH.   +10 more
europepmc   +1 more source

Recurrent somatic mutations of FAT family cadherins induce an aggressive phenotype and poor prognosis in anaplastic large cell lymphoma. [PDF]

Br J Cancer
Villa M, Sharma GG, Malighetti F, Mauri M, Arosio G, Cordani N, Lobello C, Larose H, Pirola A, D'Aliberti D, Massimino L, Criscuolo L, Pagani L, Chinello C, Mastini C, Fontana D, Bombelli S, Meneveri R, Lovisa F, Mussolin L, Janikova A, Pospíšilová Š, Turner SD, Inghirami G, Magni F, Urso M, Pagni F, Ramazzotti D, Piazza R, Chiarle R, Gambacorti-Passerini C, Mologni L.   +31 more
europepmc   +1 more source

GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas. [PDF]

Am J Hum Genet
Ren J, Cui Z, Jiang C, Wang L, Guan Y, Ren Y, Zhang S, Tu T, Yu J, Li Y, Duan W, Guan J, Wang K, Zhang H, Xing D, Kahn ML, Zhang H, Hong T.   +17 more
europepmc   +1 more source