Results 61 to 70 of about 173,415 (296)

Heart-beat perception, panic/somatic symptoms and anxiety sensitivity in children

, 2003
There is considerable evidence implicating heart-beat perception (HBP) accuracy and anxiety sensitivity (AS) in the development of panic in adults. However, to date there have been no studies exploring the association between HBP, AS and childhood panic ...
Eley, Thalia C., Clark, David M., Gregory, Alice M., Ehlers, Anke, Stirling, Lucy   +4 more
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mediating effect of sleep quality between somatic symptoms and severity of depression in patients with depression

Zhongguo Linchuang Yixue
ObjectiveTo explore the mediating effect of sleep quality between somatic symptoms and severity of depression in patients with depression. MethodsA total of 384 drug-naive patients diagnosed with depression were recruited from the Department of ...
Xiaotong LI, Zexin ZHAO, Ye LIU, Haibin LI, Xiao HUANG   +4 more
doaj   +1 more source

Chronic functional somatic symptoms: a single syndrome? [PDF]

, 2004
Contains fulltext : 59247.pdf (Publisher’s version ) (Open Access)BACKGROUND: Reliable longitudinal data of patients with functional somatic symptoms in general practice are lacking.
Lisdonk, E.H. van de, Lucassen, P.L.B.J., Bor, J.H.J., Olde Hartman, T.C., Weel, C. van   +4 more
core  

Childhood Trauma and Adult Somatic Symptoms [PDF]

, 2023
OBJECTIVE: Childhood trauma is a key public health risk factor for developing physical illness. This study examined how childhood abuse and neglect predict adult somatic symptoms assessed retrospectively and in real-time.
Hanna Eilers, Jeronimus, Bertus, Eilers, Hanna, Aan Het Rot, Marije, Bertus F. Jeronimus, Marije aan het Rot, Aan Het Rot, Marije; id_orcid, Jeronimus, Bertus; id_orcid   +7 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Depression during multiple sclerosis relapse: relation todisability and relapse severity [PDF]

Medicinski Glasnik, 2016
Aim To examine the presence of depressive symptoms in patients with multiple sclerosis relapse and its relation to disability and relapse severity.
Selma Šabanagić-Hajrić, Enra Suljić, Gorana Sulejmanpašić-Arslanagić   +2 more
doaj   +1 more source