Results 81 to 90 of about 1,689,456 (287)

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Chronic functional somatic symptoms: a single syndrome? [PDF]

, 2004
Contains fulltext : 59247.pdf (Publisher’s version ) (Open Access)BACKGROUND: Reliable longitudinal data of patients with functional somatic symptoms in general practice are lacking.
Lisdonk, E.H. van de, Lucassen, P.L.B.J., Bor, J.H.J., Olde Hartman, T.C., Weel, C. van   +4 more
core   +1 more source

Detection rate and characteristics of adult outpatients with multiple somatic symptoms of general hospital in Beijing

, 2019
Objective: To explore the detection rate and clinical characteristics of multiple somatic symptoms among adult outpatients in cardiology, neurology and GI clinics.
Hu, Yongdong, Yang, Xiang Yun, Zhang, Yi, Cao, Ruixiang, Cui, Feihuan, He, Jianhua, Gao, Jian, Li, Xiaoqi, Wang, Pengchong, Han, Xueqing, Cui, Shaojuan, Li, Zhan-Jiang, Sun, Jing, Tan, Ling, Zu, Si   +14 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Empirical assessment of functional somatic disorder (FSD): frequency, applicability, and diagnostic refinement in a population-based sample

BMC Medicine
Background Persistent and troublesome physical symptoms are common and can, regardless of their cause, greatly impair patients’ quality of life. Reflecting complex brain-body interactions, they are observed across all healthcare specialties, commonly ...
Abigail Smakowski, Judith Rosmalen, Bernd Löwe, Christopher Burton, Anne Toussaint   +4 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

The predictive value of somatic and cognitive depressive symptoms for cytokine changes in patients with major depression

, 2014
Katharina Dannehl,1 Winfried Rief,1 Markus J Schwarz,2 Annika Hennings,1 Sabine Riemer,1 Verena Selberdinger,3 Theresa Stapf,3 Frank Euteneuer11Division of Clinical Psychology and Psychotherapy, Philipps Universität Marburg, Marburg, Germany ...
Dannehl K, Euteneuer F, Riemer S, Stapf T, Schwarz MJ, Selberdinger V, Rief W, Hennings A   +7 more
core  

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

A cross-sectional study on the relationship between interoceptive sensitivity and somatic symptoms in young bipolar disorder patients

BMC Psychiatry
Background Bipolar disorder (BD) with somatic symptoms is a prevalent and refractory clinical syndrome in young patients. Interoception is an important mechanism for coordinating internal physiological and mood states to maintain individual homeostasis ...
Jialin Lv, Hang Xu, Juan Li, Lin Sun, Guohui Zhu, Weiwen Wang   +5 more
doaj   +1 more source

The Mediating Role of Somatic Symptoms in the Effect of Depression on Problem-Solving Skills

Psychiatry and Clinical Psychopharmacology
Background: Major depressive disorder (MDD) is a serious mental disorder that is common worldwide and is associated with somatic symptoms. Cognitive and behavioral problems caused by depression can negatively affect problem-solving skills, and somatic ...
Doğancan Sönmez, Bülent Bahçeci
doaj   +1 more source