Results 111 to 120 of about 138,830 (301)

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Diversity of intrinsic frequency encoding patterns in rat cortical neurons : mechanisms and possible functions [PDF]

, 2010
Extracellular recordings of single neurons in primary and secondary somatosensory cortices of monkeys in vivo have shown that their firing rate can increase, decrease, or remain constant in different cells, as the external stimulus frequency increases ...
Robinson, Hugh P. C., Kang, Jing, Ph.D., Feng, Jianfeng, Jianfeng Feng, Robinson Hugh P. C., Hugh P C Robinson, Kang Jing, Jing Kang, Feng Jianfeng   +8 more
core   +2 more sources

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source

The neural mechanisms of reliability weighted integration of shape information from vision and touch [PDF]

, 2011
Helbig HB, Ernst MO, Ricciardi E, et al. The neural mechanisms of reliability weighted integration of shape information from vision and touch. NeuroImage. 2011;60(2):1063-1072.Behaviourally, humans have been shown to integrate multisensory information in
Pietrini, Pietro, Pietro Pietrini, Mayer, K., Mayer, Katja M., Johannes Schultz, Ricciardi, Emiliano, Schultz, Johannes, Ernst, M., Katja M. Mayer, Schultz, J., Noppeney U., Ricciardi, E., Ernst MO, Noppeney, U., Pietrini, P., Ernst, Marc O., Axel Thielscher, Helbig HB, Marc O. Ernst, Thielscher, Axel, Mayer KM, Schultz J, Emiliano Ricciardi, Thielscher, A., Ricciardi, E, Hannah B. Helbig, Pietrini, P, Uta Noppeney, Thielscher A, Helbig, H., Helbig, Hannah B., Noppeney, Uta   +31 more
core   +1 more source

A Two‐Stage Characterization Pipeline and Open‐Source Framework for Reproducible Tactile Sensing

Advanced Intelligent Systems, EarlyView.
The same soft tactile sensor returns different numbers when embodied in different robots. This is an Embodiment Gap that no shared framework currently captures transparently. A two‐stage characterization pipeline, paired with a FAIR open‐source digital datasheet, decouples intrinsic sensor behavior from embodiment effects and condenses cross‐laboratory
Matteo Lo Preti, Weng Buxiu, Petr Trunin, Muhammad Sunny Nazeer, Lucia Beccai, Perla Maiolino, Cecilia Laschi   +6 more
wiley   +1 more source

A Soft Robotic Finger With Deep Learning‐Enhanced Tactile Sensing for Texture and Softness Recognition

Advanced Intelligent Systems, EarlyView.
Inspired by human touch, a tendon‐driven soft robotic finger combines multimodal tactile sensing and deep learning to simultaneously perceive texture and softness on deformable surfaces. A CNN‐LSTM model fuses pressure, accelerometer, and gyroscope signals to accurately classify material properties, achieving up to 95.4% texture and 97.0% softness ...
Gorkem Anil Al, Arya Shabani, Nicos Hadjigeorgiou, James Fant‐Male   +3 more
wiley   +1 more source

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

Cortical Thickness and White Matter Surface Morphology in Tourette Syndrome: A Cohort Study

Annals of Neurology, EarlyView.
Objective To examine cortical thickness and white matter surface morphology in a large sample of individuals with Tourette syndrome (TS) and neurotypical controls across the lifespan, and to assess associations with symptom severity, comorbidities, and medication use.
Sahar Delavari, Adam C. Frank, Ravi Bansal, Flora M. Vaccarino, Robert A. King, Paul Lombroso, Lawrence Scahill, James F. Leckman, Bradley S. Peterson   +8 more
wiley   +1 more source

Atypical Cerebellar Responses are Associated with Altered Neural Habituation during Sensory Stimulation in Autism

Autism Research, EarlyView.
ABSTRACT Sensory processing atypicalities are highly prevalent in autistic youth; yet, the neural mechanisms underlying these differences are not well understood. While the cerebellum plays a key role in sensorimotor coordination and is structurally and functionally atypical in the autistic brain, it has been overlooked in research investigating ...
Melis E. Cakar, Kaitlin K. Cummings, Susan Y. Bookheimer, Mirella Dapretto, Shulamite A. Green   +4 more
wiley   +1 more source

Use of the Brain-gauge Somatosensory Assessment for Monitoring Recovery from Concussion: A Case Study

, 2018
Objectives: To determine if Brain Gauge somatosensory metrics would adequately reflect an individual’s recovery. Design: Prospective case study of Ms ‘K’.
Tommerdahl, M, Hume, P, King, DA
core   +1 more source