Results 121 to 130 of about 138,830 (301)

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

On the Geometry of Somatosensory Representations in the Cortex

NeuroImage
Abstract It is well-known that cortical areas specializing in the processing of somatosensory information from different parts of the body are arranged in an orderly manner along the cortex. It is also generally accepted that in the cortex, somatosensory information is initially processed in the primary somatosensory cortex and from ...
Noam Saadon-Grosman, Tsahi Asher, Yonatan Loewenstein   +2 more
openaire   +3 more sources

Perinatal Western‐style diet exposure associated with altered sensory functional connectivity in infant Japanese macaques

Physiological Reports
Sensory processing disorder (SPD) is a neurodevelopmental condition characterized by impaired sensory discrimination and responsivity. Although the causes and neural correlates of SPD remain poorly understood, prenatal influences should be considered, as
Samantha Papadakis, Eric Feczko, Julian S. B. Ramirez, Oscar Miranda‐Dominguez, Darrick Sturgeon, Thomas J. Madison, Anders J. Perrone, Eric Earl, AJ Mitchell, Geoffrey A. Dunn, Elinor L. Sullivan, Damien A. Fair   +11 more
doaj   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

Epileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini, Evripidis Pityrigkas, Zoi Kallia, Georgia Pepe, Antonis Frontistis, Dimitrios Profer, Vasilios Kimiskidis   +6 more
wiley   +1 more source

Direct cortical stimulation–evoked symptoms in the human temporal pole: A systematic review

Epileptic Disorders, EarlyView.
Abstract The temporal pole represents a key node within temporolimbic networks and may contribute to seizure generation in temporal lobe epilepsy. Direct cortical stimulation (DCS), performed during intracranial presurgical evaluation, is a valuable method for delineating the seizure onset zone by reproducing electro‐clinical features of a patient's ...
Yulia Novitskaya, Andreas Schulze‐Bonhage   +1 more
wiley   +1 more source

Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review

Epileptic Disorders, EarlyView.
Abstract Objective A systematic review was conducted to synthesize current anatomo‐clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence‐based guidance for interpreting this ictal semiology during presurgical evaluation.
Mihai Dragos Maliia, Fabrice Bartolomei, Fabienne Picard   +2 more
wiley   +1 more source

The somatosensory cortex receives information about motor output

During voluntary movement, the somatosensory system not only passively receives signals from the external world but also actively processes them via interactions with the motor system.
Umeda, Tatsuya, Isa, Tadashi, Nishimura, Yukio   +2 more
core  

Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments for seizures remain largely ineffective.
Dongjun Guo, Lirong Han, Nicholas R. Rensing, Laura A. Jansen, Michael Wong   +4 more
wiley   +1 more source

Somatosensory Responses

, 2017
After a peripheral somatosensory stimulus, such as a touch to the finger, a compound action potential volley begins to travel along the peripheral nerve, first to the spinal cord, and then onward to the thalamus and somatosensory cortex.
Aina Puce, Riitta Hari
core   +1 more source