Results 61 to 70 of about 645,997 (394)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

The cutaneous 'rabbit' illusion affects human primary sensory cortex somatopically [PDF]

, 2006
We used functional magnetic resonance imaging (fMRI) to study neural correlates of a robust somatosensory illusion that can dissociate tactile perception from physical stimulation.
Blankenburg, F., Deichmann, R., Driver, J., Rees, G., Ruff, C.C.   +4 more
core  

Transcranial magnetic stimulation disrupts the perception and embodiment of facial expressions [PDF]

, 2008
Copyright © 2008 Society for Neuroscience and the authors. The The Journal of Neuroscience uses a Creative Commons Attribution-NonCommercial-ShareAlike licence: http://creativecommons.org/licenses/by-nc-sa/4.0/.Theories of embodied cognition propose that
Duchaine, BC, Garrido, L, Pitcher, D, Walsh, V   +3 more
core   +1 more source

Neural basis of somatosensory target detection independent of uncertainty, relevance, and reports

eLife, 2019
Research on somatosensory awareness has yielded highly diverse findings with putative neural correlates ranging from activity within somatosensory cortex to activation of widely distributed frontoparietal networks. Divergent results from previous studies
Pia Schröder, Timo Torsten Schmidt, Felix Blankenburg   +2 more
doaj   +1 more source

Critical Period Inhibition of NKCC1 Rectifies Synapse Plasticity in the Somatosensory cortex and Restores Adult Tactile Response Maps in Fragile X Mice

Molecular Psychiatry, 2018
Sensory perturbations in visual, auditory and tactile perception are core problems in fragile X syndrome (FXS). In the Fmr1 knockout mouse model of FXS, the maturation of synapses and circuits during critical period (CP) development in the somatosensory ...
Qionger He, Erica D. Arroyo, Samuel N. Smukowski, Jian Xu, C. Piochon, J. Savas, C. Portera-Cailliau, A. Contractor   +7 more
semanticscholar   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source

Voxel-based lesion-symptom mapping of stroke lesions underlying somatosensory deficits

NeuroImage: Clinical, 2016
The aim of this study was to investigate the relationship between stroke lesion location and the resulting somatosensory deficit. We studied exteroceptive and proprioceptive somatosensory symptoms and stroke lesions in 38 patients with first-ever acute ...
Sarah Meyer, Simon S. Kessner, Bastian Cheng, Marlene Bönstrup, Robert Schulz, Friedhelm C. Hummel, Nele De Bruyn, Andre Peeters, Vincent Van Pesch, Thierry Duprez, Stefan Sunaert, Maarten Schrooten, Hilde Feys, Christian Gerloff, Götz Thomalla, Vincent Thijs, Geert Verheyden   +16 more
doaj   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Inhibitory synaptogenesis in mouse somatosensory cortex [PDF]

Cerebral Cortex, 1997
It is widely believed that inhibitory synapses are not present or present in only small numbers in the rodent cerebral cortex during the early postnatal period when the cortex is being innervated by thalamocortical fibers. Quantitative electron microscopy was carried out on the posteromedial barrel subfield of mouse somatosensory cortex from postnatal ...
DeFelipe, Javier, Marco, P., Fairén, Alfonso, Jones, E. G.   +3 more
openaire   +3 more sources

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care &Research, Accepted Article.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high magnitude stress.
Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium   +15 more
wiley   +1 more source