Results 121 to 130 of about 309,846 (286)

Decoding Epileptogenesis in a Reduced State Space [PDF]

open access: yesarXiv, 2017
We describe here the recent results of a multidisciplinary effort to design a biomarker that can actively and continuously decode the progressive changes in neuronal organization leading to epilepsy, a process known as epileptogenesis. Using an animal model of acquired epilepsy, wechronically record hippocampal evoked potentials elicited by an auditory
arxiv  

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

open access: yesAging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik   +20 more
wiley   +1 more source

Tactile spatial attention enhances gamma-band activity in somatosensory cortex and reduces low-frequency activity in parieto-occipital areas. [PDF]

open access: yes, 2006
We investigated the effects of spatial-selective attention on oscillatory neuronal dynamics in a tactile delayed-match-to-sample task. Whole-head magnetoencephalography was recorded in healthy subjects while dot patterns were presented to their index ...
Bauer, M   +3 more
core  

Somatosensory evoked potentials in pure sensory stroke and related conditions. [PDF]

open access: bronze, 1985
R. K. Robinson   +3 more
openalex   +1 more source

Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Whereas biased agonism on the 5‐HT2A receptor has been ascribed to hallucinogenic properties of psychedelics, no information about biased inverse agonism on this receptor is available. In schizophrenia, increased 5‐HT2A receptor constitutive activity has been suggested, highlighting the therapeutic relevance of inverse ...
Itziar Muneta‐Arrate   +4 more
wiley   +1 more source

Long‐Term Benefit of Thalamic Deep Brain Stimulation in POLR3A Mutation‐Associated Action Tremor

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Martina Minnerop   +10 more
wiley   +1 more source

Psilocybin as a novel treatment for chronic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey   +3 more
wiley   +1 more source

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