Results 191 to 200 of about 309,846 (286)
The Journal of Physiology, EarlyView.Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley +1 more source
Presynaptic quantal size enhancement counteracts post‐tetanic release depression
The Journal of Physiology, EarlyView.Abstract figure legend Sustained high‐frequency stimulation decreases the number of synaptic vesicles that fuse per action potential at the Drosophila neuromuscular junction. However, the postsynaptic response remains largely unchanged. An increased postsynaptic response to individual vesicles, likely driven by an increase in vesicle size resulting ...
Anu G. Nair +5 more
wiley +1 more source
Detection of neurological injury using time-frequency analysis of the somatosensory evoked potential
, 1996 Jeffrey C. Braun +2 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Sensory hair cells of the inner ear and lateral‐line system exhibit strong synaptic‐vesicle enrichment at the presynapse, around specialized structures called ribbons. We find that hair cells in the zebrafish lateral‐line system rely on the kinesin motor protein Kif1a and microtubules to enrich synaptic vesicles at presynaptic ...
Sandeep David +7 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Monomeric and multimeric α‐synuclein were purified from HEK cells and delivered to lamprey reticulospinal (RS) synapses via axonal microinjection, followed by stimulation (20 Hz, 5 min). Ultrastructural analysis showed that both α‐synuclein species impaired intracellular vesicle trafficking, leading to synaptic vesicle loss and ...
Cristina Román‐Vendrell +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Basket cells represent critical building blocks of neuronal circuits in cortical regions by providing GABAergic innervation to the perisomatic region of their postsynaptic partners. In the mouse prelimbic cortex, the two basket cell types expressing parvalbumin or cholecystokinin/type I cannabinoid receptor receive unitary ...
Zsuzsanna Fekete +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend During development, Intersectin‐1 (Itsn1) translocates near voltage‐gated calcium channels (VGCCs) to enhance Ca2+‐dependent replenishment of readily releasable synaptic vesicles (SVs). In the presynaptic terminal, SVs undergo a cycle involving formation (step 1), docking (step 2), exocytosis (step 3), endocytosis (step 4) and ...
Yi‐Mei Yang +13 more
wiley +1 more source