Results 221 to 230 of about 43,726 (267)
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Somatostatin and Somatostatin Receptor Physiology
Endocrine, 2003Since the discovery of somatostatin (SST) over three decades ago, its ubiquitous distribution and manifold functions are still being documented. SST is synthesized in the hypothalamus and transported to the anterior pituitary gland where it tonicaly inhibits GH and TSH secretion as well as being responsible for GH pulsatile release.
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Critical reviews in neurobiology, 1992
The neuropeptide somatostatin (SRIF) is a neurotransmitter in the brain that exerts physiological actions including the modulation of Ca2+ and K+ conductances, neuronal cell firing, neurotransmitter release, and certain behaviors such as locomotion and cognitive functions.
K, Raynor, T, Reisine
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The neuropeptide somatostatin (SRIF) is a neurotransmitter in the brain that exerts physiological actions including the modulation of Ca2+ and K+ conductances, neuronal cell firing, neurotransmitter release, and certain behaviors such as locomotion and cognitive functions.
K, Raynor, T, Reisine
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The somatostatin receptor family
Life Sciences, 1995The diverse biological effects of somatostatin (SST) are mediated through a family of G protein coupled receptors of which 5 members have been recently identified by molecular cloning. This review focuses on the molecular biology, pharmacology, expression, and function of these receptors with particular emphasis on the human (h) homologs.
Y C, Patel +5 more
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Somatostatin receptors in gliomas
Journal of Physiology-Paris, 2000Gliomas differ from non-malignant glial cells in the overexpression or mutations of genes involved in cell cycle or growth regulation. One example is the overexpression of the somatostatin receptor subtype 2 (sst2), especially of the splice variant sst2A. The reasons for this overexpression are not known.
J, Held-Feindt +3 more
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Somatostatin and somatostatin receptors in fish growth
General and Comparative Endocrinology, 2010Multiple forms of somatostatin (SS) and SS receptors (SSTR) are produced widely in the tissues of fish and interact to coordinate numerous physiological processes. Insight into their role in growth regulation emerged from studies of abnormal growth and of whole animals.
Mark A, Sheridan, Alison L, Hagemeister
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Molecular biology of somatostatin receptors
Trends in Neurosciences, 1993The neuropeptide somatostatin (SRIF) has diverse physiological actions in the brain and endocrine organs. A family of SRIF receptors has recently been cloned that may mediate the distinct biological effects of SRIF. These receptors have a high degree of amino acid sequence similarity among themselves, but their sequences are different from any other ...
G I, Bell, T, Reisine
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Somatostatin Receptors in the Orbits
Clinical Nuclear Medicine, 1995In-111 pentetreotide has been recommended for the detection of somatostatin receptor (SSR) positive tumors. Sites with increased numbers of activated lymphocytes may also show In-111 pentetreotide with Graves' ophthalmopathy (GO) compared to various other orbital disorders.
DURAK, I +4 more
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2002
Abstract Somatostatin (Somatotropin-release inhibiting factor, SRIF) produced by neuronal, neuroendocrine, inflammatory and immune cells as well as tumours, produces its many (patho)physiological functions through activation of specific cell membrane receptors.
Patrick P A Humphrey, Daniel Hoyer
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Abstract Somatostatin (Somatotropin-release inhibiting factor, SRIF) produced by neuronal, neuroendocrine, inflammatory and immune cells as well as tumours, produces its many (patho)physiological functions through activation of specific cell membrane receptors.
Patrick P A Humphrey, Daniel Hoyer
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Evolutionary history of the somatostatin and somatostatin receptors
Journal of Genetics, 2009Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus, Xenopus tropicalis, Gallus gallus, Monodelphis ...
Muhammad, Moaeen-ud-Din, Li Guo, Yang
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2010
Somatostatin receptor PET-CThemploys positron emitting tracers (68Ga-DOTA-peptides) that specifically bind to somatostatin receptors (ssr) expressed on tumor cell surface and has been used mainly for the assessment of neuroendocrine tumors (NETs).
AMBROSINI, VALENTINA +3 more
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Somatostatin receptor PET-CThemploys positron emitting tracers (68Ga-DOTA-peptides) that specifically bind to somatostatin receptors (ssr) expressed on tumor cell surface and has been used mainly for the assessment of neuroendocrine tumors (NETs).
AMBROSINI, VALENTINA +3 more
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