Results 161 to 170 of about 69,057 (285)

The new WHO classification of gastrointestinal neuroendocrine tumors and immunohistochemical expression of somatostatin receptor 2 and 5. [PDF]

Exp Ther Med, 2021
Popa O, Taban SM, Pantea S, Plopeanu AD, Barna RA, Cornianu M, Pascu AA, Dema ALC.   +7 more
europepmc   +1 more source

Prospects of Targeting the Gastrin Releasing Peptide Receptor and Somatostatin Receptor 2 for Nuclear Imaging and Therapy in Metastatic Breast Cancer

, 2017
Simone U. Dalm, Willemijne A.M.E. Schrijver, Anieta M. Sieuwerts, Maxime P. Look, Angelique C. J. Ziel – van der Made, Vanja de Weerd, John W.M. Martens, P. J. van Diest, Marion de Jong, Carolien H. M. van Deurzen   +9 more
openalex   +2 more sources

Incretin hormones and obesity

The Journal of Physiology, EarlyView.
Abstract figure legend The incretin system in obesity. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) (yellow) and glucagon‐like peptide‐1 (GLP‐1) (blue) are produced by the proximal and distal small intestinal epithelium, where they are released postprandially into the bloodstream to modulate a myriad of physiological and ...
Constanza Alcaino, Frank Reimann, Fiona M. Gribble   +2 more
wiley   +1 more source

The potential of somatostatin receptor 2 as a novel therapeutic target in salivary gland malignant tumors. [PDF]

J Cancer Res Clin Oncol, 2021
Meirovitz A, Shouchane-Blum K, Maly A, Bersudski E, Hirshoren N, Abrams R, Popovtzer A, Orevi M, Weinberger J.   +8 more
europepmc   +1 more source

J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine [PDF]

Andy Kuo, Mohammad Zafar Imam, R. Li, Li Lin, A. Raboczyj, Ana Elisa Böhmer, Janet R. Nicholson, Laura Corradini, Maree T. Smith   +8 more
openalex   +1 more source

Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Table S1 from Upregulation of Somatostatin Receptor Type 2 Improves ¹⁷⁷Lu-DOTATATE Therapy in Receptor-Deficient Pancreatic Neuroendocrine Tumor Model [PDF]

, 2023
Rupali Sharma, Bhargav Earla, Kwamena E. Baidoo, Martha A. Zeiger, James P. Madigan, Freddy E. Escorcia, Samira M. Sadowski   +6 more
openalex   +1 more source

Single‐cell transcriptomics of human organoid‐derived enteroendocrine cell populations from the small intestine

The Journal of Physiology, EarlyView.
Abstract figure legend Human intestinal organoids were genetically modified to express a fluorescent protein in enteroendocrine cells (EECs), which were then separated by flow cytometry and analysed by single‐cell RNA sequencing. High numbers of human EECs were thereby available for cluster analysis and differential gene expression, revealing ...
Christopher A. Smith, Van B. Lu, Rula Bany Bakar, Emily Miedzybrodzka, Adam Davison, Deborah Goldspink, Frank Reimann, Fiona M. Gribble   +7 more
wiley   +1 more source

Inhibitory circuit motifs of cortical somatosensory layer 5 SST interneurons are uniform within layers but specific across layers

The Journal of Physiology, EarlyView.
Abstract figure legend In our study we wanted to discover inhibitory circuits targeting layer 5 (L5) somatostatin (SST)‐expressing neurons. As putative presynaptic cells we chose parvalbumin (PV) and vasoactive intestinal polypeptide (VIP)‐expressing interneurons (IN). Previous studies showed that in L2/3 SST IN are targeted by PV and VIP cells.
Felix Preuss, Florian Walker, Martin Möck, Mirko Witte, Jochen F. Staiger   +4 more
wiley   +1 more source

Understanding the influence of lipid bilayers and ligand molecules in determining the conformational dynamics of somatostatin receptor 2. [PDF]

Sci Rep, 2021
Nagarajan SK, Babu S, Kulkarni SA, Vadivelu A, Devaraju P, Sohn H, Madhavan T.   +6 more
europepmc   +1 more source

Coexpression of Somatostatin Receptor Subtype 5 Affects Internalization and Trafficking of Somatostatin Receptor Subtype 2 [PDF]

, 2007
Nadder Sharif, Louis Gendron, Julia Wowchuk, Philippe Sarret, Jean Mazella, Alain Beaudet, Thomas Stroh   +6 more
openalex   +1 more source