Results 61 to 70 of about 69,057 (285)

Therapeutic sequences in patients with grade 1−2 neuroendocrine tumors (NET): an observational multicenter study from the ELIOS group [PDF]

, 2019
Purpose: Many different treatments are suggested by guidelines to treat grade 1−2 (G1−G2) neuroendocrine tumors (NET). However, a precise therapeutic algorithm has not yet been established.
Badalamenti, G., Bianco, A., Colao, A., De Divitiis, C., Di Maio, S., Di Sarno, A., Dolce, P., Faggiano, A., Guarnotta, V., Leo, S., Mocerino, C., Modica, R., Ottaviano, M., Palmieri, G., Puliafito, I., Riccardi, F., Tafuto, S., Tozzi, L.   +17 more
core   +1 more source

Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High‐Volume Center

Annals of Gastroenterological Surgery, EarlyView.
In patients with NELM, those with < 8 liver metastases and G1/2 tumors are the favorable candidates for liver resection. The important point of this study is that the patients who do not meet the above criteria should be considered for multidisciplinary treatment because of their extremely shorter recurrence‐free period.
Daisuke Asano, Toshitaka Sugawara, Keiichi Akahoshi, Shotaro Gan, Shohei Motohashi, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Atsushi Kudo, Daisuke Ban   +9 more
wiley   +1 more source

Expression of somatostatin receptors, angiogenesis and proliferation markers in pituitary adenomas: an immunohistochemical study with diagnostic and therapeutic implications

Swiss Medical Weekly, 2013
PRINCIPLES: Pituitary adenomas are common intracranial neoplasms that generate symptoms as a result of either mass effect or the increased production of pituitary hormones.
Alejandra Magagna-Poveda, Henning Leske, Christoph Schmid, René Bernays, Elisabeth Rushing   +4 more
doaj   +1 more source

Carcinoid Heart Disease: How to Diagnose and Treat in 2020?

Clinical Medicine Insights: Cardiology, 2020
Neuroendocrine tumors (NETs, originally termed “carcinoids”) create a relatively rare group of neoplasms with an approximate incidence rate of 2.5 to 5 cases per 100 000 persons.
Barbara Bober, Marek Saracyn, Maciej Kołodziej, Łukasz Kowalski, Elżbieta Deptuła-Krawczyk, Waldemar Kapusta, Grzegorz Kamiński, Olga Mozenska, Jacek Bil   +8 more
doaj   +1 more source

Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi, Kentaro Miyake, Kota Sahara, Jun Yamamoto, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Ryusei Matsuyama, Itaru Endo   +9 more
wiley   +1 more source

Molecular simulations of SSTR2 dynamics and interaction with ligands

Scientific Reports, 2023
The cyclic peptide hormone somatostatin regulates physiological processes involved in growth and metabolism, through its binding to G-protein coupled somatostatin receptors.
Silvia Gervasoni, Camilla Guccione, Viviana Fanti, Andrea Bosin, Giancarlo Cappellini, Bruno Golosio, Paolo Ruggerone, Giuliano Malloci   +7 more
doaj   +1 more source

Bio‐Inspired Pancreas With Microfluidic Multi‐Component Hydrogel Microfibers for Exploring Pancreatic Exocrine and Endocrine Interactions

Aggregate, EarlyView.
A bionic pancreas model incorporating core‐shell microfibers that encapsulate pancreatic stellate cells (PSCs) and β‐cells provides valuable insights into PSCs activation, cell‐cell interactions, and diabetes progression. Furthermore, the potential of this bio‐inspired pancreas for drug screening is demonstrated by testing with a glucagon‐like peptide ...
Zhikun Huan, Zhiqiang Luo, Jingbo Li, Yunru Yu, Ling Li   +4 more
wiley   +1 more source

An Update on DOTA-Peptides PET Imaging and Potential Advancements of Radioligand Therapy in Intracranial Meningiomas

Life
Meningiomas arise from the meningeal layers covering the central nervous system structures. Although most are benign, meningiomas can still cause neurological morbidity due to the mass effect and compression of the surrounding parenchyma.
Viviana Benfante, Ignazio Gaspare Vetrano, Muhammad Ali, Pierpaolo Purpura, Cesare Gagliardo, Paola Feraco, Costanza Longo, Tommaso Vincenzo Bartolotta, Patrizia Toia, Oriana Calisto, Albert Comelli, Massimo Midiri, Pierpaolo Alongi   +12 more
doaj   +1 more source

Characterization of Somatostatin Receptor Subtype 2 Expression in Stably Transfected A-427 Human Cancer Cells

Molecular Imaging, 2007
Although radiolabeled somatostatin analogs have become highly prevalent in the diagnosis and treatment of somatostatin receptor subtype (sst)-positive tumors, there are relatively few options with respect to sst-positive tumor cell lines and animal ...
Jesse J. Parry, Martin Eiblmaier, Rebecca Andrews, Laura A. Meyer, Ryuji Higashikubo, Carolyn J. Anderson, Buck E. Rogers   +6 more
doaj   +1 more source

Towards a Radio-guided Surgery with $\beta^{-}$ Decays: Uptake of a somatostatin analogue (DOTATOC) in Meningioma and High Grade Glioma

, 2014
A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the deployment of ...
BELLINI, Fabio, Bocci, Valerio, Chiodi, Giacomo, COLLAMATI, FRANCESCO, Cremonesi, Marta, DE LUCIA, Erika, FACCINI, Riccardo, Ferrari, Mahila E., Frallicciardi, Paola M., Grana, Chiara M., Marafini, Michela, Mattei, Ilaria, Morganti, Silvio, PATERA, Vincenzo, PEPE, ALESSANDRA, PIERSANTI, LUCA, PINCI, davide, Recchia, Luigi, RUSSOMANDO, ANDREA, SARTI, ALESSIO, SCIUBBA, Adalberto, SENZACQUA, MARTINA, SOLFAROLI CAMILLOCCI, ELENA, VOENA, Cecilia   +23 more
core   +1 more source