Results 81 to 90 of about 69,057 (285)
Molecules, 2020 Targeted radionuclide therapy of somatostatin receptor (SST)-expressing tumors is only partially addressed by the established somatostatin analogs having an affinity for the SST subtype 2 (SST2).
Rosalba Mansi +5 more
doaj +1 more source
On the G-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation [PDF]
, 2013 The modulatory role of allosteric receptor-receptor interactions in the pain pathways of the Central Nervous System and the peripheral nociceptors has become of increasing interest.
Agnati, Luigi F +6 more
core +3 more sources
Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)
ELECTROPHORESIS, EarlyView.ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
iRADIOLOGY, EarlyView.The article reviews the application of positron emission tomography/magnetic resonance imaging (PET/MRI) in pelvic tumors such as endometrial cancer, cervical cancer, ovarian cancer, prostate cancer, and bladder cancer. We summarize the comparative studies on the clinical application between PET/CT and PET/MRI to highlight the advantages and ...
Hui Yang +7 more
wiley +1 more source
Pituitary gigantism due to a novel AIP germline splice-site variant
Endocrine OncologyPituitary gigantism is a rare pediatric disorder caused by excess growth hormone (GH) secretion. In almost 50% of cases, a genetic cause can be identified, with pathogenic variants in the aryl hydrocarbon receptor-interacting protein (AIP) gene being the
Elisa Lamback +6 more
doaj +1 more source
The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin
European Journal of Histochemistry, 2009 Somatostatin is a peptide hormone that exerts antisecretory and antiproliferative activities on some human tumors. The Ku70/86 heterodimer acts as regulatory subunit of the DNA dependent protein kinase and its DNA binding activity mediates DNA double ...
S Pucci +4 more
doaj +1 more source
Molecular theranostics: principles, challenges and controversies
Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley +1 more source
New cross-roads for second line medical therapy in acromegaly [PDF]
Archives of the Balkan Medical Union, 2018 Acromegaly is a complex disorder caused by growth hormone excess mostly due to a pituitary adenoma. Surgery represents the first option but rate of long time success is almost 50% thus the patients need other therapies.
Adina Ghemigian +5 more
doaj
IGF-I influences everolimus activity in medullary thyroid carcinoma [PDF]
, 2015 Context: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus,
degli Uberti, Ettore C. +9 more
core +1 more source