Results 31 to 40 of about 231 (96)
Pharmacological Research, 2023 We evaluated the efficacy, safety, adherence, quality of life (QoL) and cost-effectiveness of long-acting growth hormone (LAGH) vs daily growth hormone (GH) preparations in the treatment of growth hormone deficiency (GHD) in children. Systematic searches
Chiara Mameli +11 more
doaj +1 more source
Efficacy and Safety of Somapacitan Relative to Somatrogon and Lonapegsomatropin in Pediatric Growth Hormone Deficiency: Systematic Literature Review and Network Meta-analysis [PDF]
Advances in TherapyLasse De Fries Jensen +2 more
exaly +2 more sources
JCRPEObjective: To report real-world 6- and 12-month outcomes in children with growth hormone deficiency (GHD) treated with somatrogon or somatropin, including those who transitioned from somatropin to somatrogon.
Kübra Şen Küçük +5 more
doaj +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.This network meta‐analysis of 18 randomized controlled trials demonstrates that once‐weekly long‐acting growth hormone formulations offer comparable efficacy and safety to daily somatropin for paediatric growth hormone deficiency. While discontinuation rates remain similar, agent selection should consider specific local tolerability profiles, notably ...
Amir Abadi +8 more
wiley +1 more source
Drug Testing and Analysis, Volume 18, Issue 7, Page 811-820, July 2026.After evaluating the compatibility of the GH analogue redalsomatropin alfa with approved doping control immunoassays for rhGH, it was implemented into the existing detection method for somatrogon employing affinity purification with GHR‐Fc‐conjugated magnetic beads, tryptic digestion, and LC‐HRMS/MS to allow for a specific and sensitive detection ...
Katja Walpurgis +6 more
wiley +1 more source
Drug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
Drug Design, Development and Therapy, 2022 Bradley S Miller,1 Kevin CJ Yuen2 1Pediatric Endocrinology, University of Minnesota Medical School, Minneapolis, MN, USA; 2Department of Neuroendocrinology and Neurology, Barrow Pituitary Center, University of Arizona College of Medicine and Creighton ...
Miller BS, Yuen KCJ
doaj
Therapeutic Peptides, Proteins and their Nanostructures for Drug Delivery and Precision Medicine
ChemBioChem, Volume 25, Issue 8, April 16, 2024.Peptide nanostructures with tunable structural features, multifunctionality, biocompatibility and biomolecular recognition capacity enable development of targeted drug delivery tools for precision medicine applications. In this review article, we present various techniques employed for the synthesis and self‐assembly of peptides into nanostructures ...
HaRam Kim +4 more
wiley +1 more source
JCRPEObjective: Growth hormone deficiency (GHD) in children results in short stature and impaired bone health. While daily growth hormone (GH) injections are effective, they are associated with adherence challenges.
Mohammad Hosny Awad +4 more
doaj +1 more source