Results 191 to 200 of about 2,250 (205)
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Exosome‐Inhibiting Polymeric Sonosensitizer for Tumor‐Specific Sonodynamic Immunotherapy
Advanced MaterialsAbstractCombination cancer immunotherapy based on electromagnetic energy and immunotherapy shows potent anti‐cancer efficacy. However, as a factor that mediates tumor metastasis and immune suppression, the impact of tumor exosomes on therapy under electromagnetic energy stimulation remains unclear.
Jiayan Wu +5 more
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Exploring BODIPY derivatives as sonosensitizers for anticancer sonodynamic therapy
European Journal of Medicinal ChemistrySonodynamic therapy (SDT) is an emerging non-invasive and effective therapeutic modality for cancer treatment bearing benefit of deep tissue-penetration in comparison to photo-inspired therapy. However, exploring novel sonosensitizers with high sonosensitivity and desirable biosafety remains a significant challenge.
Xudong Li +8 more
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Sonodynamic therapy of cancer using novel sonosensitizers.
Anticancer research, 2007Sonodynamic therapy (SDT) of cancer is based on preferential uptake and/or retention of a sonosensitizing drug (sonosensitizer) in tumor tissues and subsequent activation of the drug by ultrasound irradiation. Ultrasound can penetrate deeply into tissues and can be focused into a small region of a tumor to activate a sonosensitizer.
Masahide, Kuroki +9 more
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Sonodynamic antitumor effect of a novel sonosensitizer on S180 solid tumor
Biopharmaceutics & Drug Disposition, 2013ABSTRACTPurpose: The purpose of this study was to evaluate the sonodynamically induced antitumor effect of a novel sonosensitizer (DVDMS) in mice bearing sarcoma 180 solid tumors. Methods: In order to determine the optimum timing of ultrasound exposure after administration of DVDMS, a three‐dimensional optical imaging system (IVIS spectrum) was used to
Caifeng, Li +5 more
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Advanced Materials
AbstractSonodynamic therapy (SDT) is a non‐invasive cancer treatment that uses ultrasound to activate sonosensitizers for selective tumor ablation. With its superior tissue penetration compared to photodynamic therapy, SDT demonstrates the potential to stimulate antitumor immune responses by modulating the tumor microenvironment.
Zuo Yang +8 more
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AbstractSonodynamic therapy (SDT) is a non‐invasive cancer treatment that uses ultrasound to activate sonosensitizers for selective tumor ablation. With its superior tissue penetration compared to photodynamic therapy, SDT demonstrates the potential to stimulate antitumor immune responses by modulating the tumor microenvironment.
Zuo Yang +8 more
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Formulation and Characterization of Sonosensitive Organic Nanoparticles
2021In den pharmazeutischen Wissenschaften scheinen nanoskalige Formulierungen die Antwort auf viele neue Therapie- und Diagnoseansätze zu sein [1]. Über 350 Studien zu verschiedenen Nanopartikelformulierungen und Indikationsgebieten werden derzeit in klinischen Studien durchgeführt, von denen allerdings nur 26 die Phase 3 erreicht haben [2]. Sie sind auch
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Editing Benzotrithiophene-Based Covalent Organic Frameworks for Developing New Sonosensitizers
ACS Applied Materials & InterfacesRecent insights into covalent organic frameworks (COFs) provide an opportunity for developing new sonosensitizers with the advantages of both small molecules and inorganic nanoagents. Herein, we synthesize two benzotrithiophene-based imine-linked COFs (BTT-DPh-COF and BTT-DPy-COF) through density-functional-theory-guided structure editing. The tailored
Chunyuan Hou +7 more
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Biomaterials
Periodontitis is a chronic disease caused by bacteria (e.g. Porphyromonas gingivalis, P.gingivalis) that currently lacks effective non-invasive treatment options. Sonodynamic therapy (SDT) is an emerging non-invasive antimicrobial therapeutic strategy.
Qi Sun +9 more
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Periodontitis is a chronic disease caused by bacteria (e.g. Porphyromonas gingivalis, P.gingivalis) that currently lacks effective non-invasive treatment options. Sonodynamic therapy (SDT) is an emerging non-invasive antimicrobial therapeutic strategy.
Qi Sun +9 more
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Sonosensitizing properties of silicon nanoparticles
2017Liubov Osminkina, Andrew Sviridov
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