Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
A renormalisation group approach to the universality of Wigner's semicircle law for random matrices with dependent entries [PDF]
We show that if the non Gaussian part of the cumulants of a random matrix model obey some scaling bounds in the size of the matrix, then Wigner's semicircle law holds.
Krajewski, Thomas
core +5 more sources
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
La idea boederiana del saber civil y su relación con el idealismo alemán
Reconocer la “filo-sophia” como tal, más acá de la Posmodernidad, significa, a partir de los estudios sorprendentes de Heribert Boeder (1928-2013) verla como un saber edificado, epocalmente, sobre una “sophia”, esto es, sobre un saber inicial acerca del ...
Martín Zubiria
doaj +1 more source
The complementarity of Plutarch’s Πῶς δεῖ τὸν νέον ποιημάτων ἀκούειν and Περὶ τοῦ ἀκούειν: Two educational ‘sessions’ (re)visited = The Complementarity of Plutarch's Quomodo adolescens poetas audire debeat and De recta ratione audiendi: Two educational ‘sessions’ (re)visited [PDF]
No abstract ...
Xenophontos, Sophia
core
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Source: Johann Christian Hallmann: Sämtliche Werke. Herausgegeben von Gerhard Spellerberg, Berlin und New York: Walter de Gruyter, 1975.
+6 more sources
Enhancements to knowledge discovery framework of SOPHIA textual case-based reasoning
Many approaches were presented recently for developing Textual Case-Based Reasoning (TCBR) applications. One of the successful approaches is SOPHisticated Information Analysis (SOPHIA), which is distinguished by its ability to work without prior ...
Islam Elhalwany +3 more
doaj +1 more source
To improve the cooling system of internal combustion engines, the utilization of the nucleate boiling heat transfer is desired. Our previous study revealed the relationship between the water nucleate boiling heat flux and dimensionless numbers.
Haoyu Chen +9 more
doaj +1 more source
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source

