Results 171 to 180 of about 2,223,665 (257)

C/EBP-β Mediates the Reversal of Sorafenib Resistance by Tunicamycin in Hepatocellular Carcinoma. [PDF]

J Hepatocell Carcinoma
Pang C, Chen J, Chu M, Chen J, Wang H, Miao H.   +5 more
europepmc   +1 more source

Recent Advances in Microwave and Ultrasound Assisted Synthesis of Quinoline Derivatives as Anticancer Agents

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Green microwave‐ and ultrasound‐assisted synthesis enables the rapid, sustainable preparation of quinoline‐based anticancer agents with improved reaction efficiency, higher yields, and enhanced biological activity. ABSTRACT Quinoline derivatives represent a privileged class of heterocyclic compounds with remarkable structural diversity and broad ...
Rohit Pal, Gurubasavaraja Swamy Purawarga Matada, Ghanshyam Teli, Manjushree B V, Vipin K. Pandey, Shourya Pratap   +5 more
wiley   +1 more source

Aurora-A drives sorafenib resistance by scaffolding stress granule assembly via phase separation. [PDF]

Proc Natl Acad Sci U S A
Kong L, Zhong F, Yu F, Wang T, Wang G, Bai Y, Xia H, Pan Z, Liu M, Zhang Y, Feng R, Zhang J, Du Y, Zhang K, Guo J, Ruan K, Yang Z.   +16 more
europepmc   +1 more source

Image_1_IL-22 signaling promotes sorafenib resistance in hepatocellular carcinoma via STAT3/CD155 signaling axis.tif

IntroductionSorafenib is currently the first-line treatment for patients with advanced hepatocellular carcinoma (HCC). Nevertheless, sorafenib resistance remains a huge challenge in the clinic.
Chidan Wan (144282), Junzhang Chen (12427704), Hui Li (32376), Xiong Cai (140594), Shiran Sun (14095587)   +4 more
core   +1 more source

Evaluating the Anticancer and Anti‐Angiogenic Efficacy of Bergaptol in 2D and 3D Tumor Microtissue Models

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Bergaptol induced cell viability inhibition, apoptosis, and cell cycle arrest in HeLa, MDA‐MB‐231, and HepG2 cancer cell lines. Furthermore, it reduced cell viability and suppressed angiogenesis in multicellular microtissues composed of cancer, endothelial, and fibroblast cells.
Buse Bekar, Handan Sevim Akan
wiley   +1 more source

Endophytic Fungi Natural Factories of Novel Bioactive Compounds

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev, Jakhongir Movlanov, Liu Wei, Wei Liu, Maksud Isokov, Santosh Kumar Bose, Fazliddin Kobilov, Zamira Djumayeva, Buston Islamov, Jamila Sherkulova, Zafar Matyakubov, Muniskhon Meylieva, Munisa Ergasheva, Diyor Abduraxmanov, Guozheng Huang, Hongchen Jiang, Kakhramon Davranov, Guohui Pan, Nigora Rustamova   +18 more
wiley   +1 more source

RPL28 mediates sorafenib resistance in hepatocellular carcinoma by downregulating CDC6 expression. [PDF]

Front Oncol
Shi Y, Chen F, Weng Y, Zeng H, Chen G.
europepmc   +1 more source

Histone Post‐Translational Modifications Regulating Ferroptosis: The Molecular Mechanisms and Disease Associations

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Ferroptosis is a form of programmed cell death characterized by iron‐dependent phospholipid peroxidation and is implicated in a wide range of human diseases. Emerging evidence highlights the critical role of epigenetic regulation in this process.
Xiaoqian Tang, Haodang Luo, Siqi Gao, Xiaocheng Liu, Qing Sun, Yanhua Zeng   +5 more
wiley   +1 more source

Nanomaterial-based strategies to overcome sorafenib resistance in hepatocellular carcinoma: from mechanistic insights to translational applications. [PDF]

Front Oncol
Huang J, Huang S, Chen W, Wang S, Zuo Z, Wu X, Deng G.   +6 more
europepmc   +1 more source

Bufalin Inhibits Melanoma Progression and Endothelial Angiogenic Phenotypes via AKT Signaling

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Introduction Bufalin (BF) exhibits anti‐tumor activity in many tumor types. However, there are few reports on BF in melanoma, and its pharmacological effects have not yet been elucidated. The present study aimed to investigate the effects of BF on melanoma and angiogenesis and to explore its possible mechanism.
Xiao xuan Zhao, Ming xin Li, Jiang xue Qu   +2 more
wiley   +1 more source