Results 121 to 130 of about 10,800,271 (244)
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, restricted interests, and repetitive behaviors. In addition to these core behavioral symptoms, gastrointestinal (GI) disorders are frequently reported, ranging from severe constipation to diarrhea.
Baptiste Ganachaud +9 more
wiley +1 more source
Competing Pathways in Heme Catalyzed Oxidations With Porphyrin‐Centered Reactivity
Heme‐catalyzed oxidations proceeding through porphyrin‐centered reactivity are quite rare. In attempts to optimize the catalytic umpolung of chloride proceeding via an isoporphyrin, we found a competing pathway. The iron(III) π‐dication readily performs alternative reactivity, leading to a bifurcation in reaction mechanisms at this point.
Silène Engbers +3 more
wiley +1 more source
This study explores how a heat‐generating Oldroyd‐B nanofluid behaves inside an annular hydromagnetic power‐generator duct with a porous, axially stretching inner cylinder. The coupled flow, heat, mass, and magnetic‐field equations are solved using the Crank–Nicolson method.
Kafunda Tuesday +2 more
wiley +1 more source
Miniaturized Droplet‐Based Adaptation of the Ames Test for High‐Throughput Mutagenicity Assessment
ABSTRACT This work presents the first demonstration of a tube‐based droplet microfluidic implementation of the Ames test, bridging single‐droplet resolution with regulatory genotoxicity testing. The Ames test is a cornerstone assay for detecting mutagenicity, but conventional plate‐ and well‐based formats suffer from high reagent consumption, low ...
Jialan Cao +3 more
wiley +1 more source
This study demonstrates that combination BL and 5‐ALA PDT does not induce detectable levels of CPD or 6–4PP photolesions in human dermal fibroblasts in vitro. Our findings contribute to the lesion‐specific genotoxic safety profile of blue light photodynamic therapy, an established research topic.ABSTRACTPhotodynamic therapy (PDT) is an established ...
Julia Stolyar +3 more
wiley +1 more source
Photocatalytic Hydrogen Evolution From Self‐Assembled Stacks of Pd–TCPP and Pt–TCPP
ABSTRACT The present work demonstrates that surfactant‐free precipitation of Pd– and Pt–TCPP in MeOH/H2O yields well‐defined supramolecular architectures (µm‐long nanorods) whose photocatalytic function tracks their metal‐dependent photophysics and stacking.
Jihyeon Kim +3 more
wiley +1 more source
ABSTRACT Objectives The first aim was to describe longitudinal changes in levator hiatus area from 21 weeks' gestation in the first pregnancy to 1 and 8 years after first delivery, according to subsequent vaginal parity in women with vaginal delivery or Cesarean section (CS) at first delivery.
F. Siafarikas +5 more
wiley +1 more source
Abstract Water is believed to be transported, at least locally, into the Earth's deep mantle via hydrous minerals. Fluorine not only tends to interact with water but also influences the stability of hydrous minerals. Thus, knowledge of its stability could be important in understanding the deep‐water cycle.
Takashi Yoshino +8 more
wiley +1 more source
Human IDO2 exhibits unique binding affinities distinct to those of human IDO1
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi +8 more
wiley +1 more source
ABSTRACT The processes involved during subduction initiation (SI) remain poorly constrained, in part due to the rarity of geological archives. Ophiolites and their underlying metamorphic soles are thought to form during subduction zone infancy and may thus provide critical constraints. Metamorphic soles are derived from oceanic crust of the lower plate
François Fournier‐Roy +11 more
wiley +1 more source

