Results 111 to 120 of about 379,550 (314)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Circular Sort: A New Improved Version of Insertion Sort Algorithm
, 2007 A new sorting algorithm, called here Circular Sort, is described. It is an improved version of the conventional Insertion Sort. It is of interest for the following reasons: it retains all the favourable features of Insertion Sort and at the same time ...
P. Y. Padhye
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Neglected Tropical Diseases: responding to calls for action from the front lines in Ethiopia
Journal of Infection in Developing Countries, 2020 Ebba Abate, John C Reeder
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
High levels of unfavourable treatment outcomes in children with drug-sensitive TB in Sierra Leone
Public Health ActionSETTING: Ola During Children’s Hospital, a tertiary-level paediatric facility affiliated with a university and located in Freetown, Sierra Leone. No published studies from Sierra Leone have evaluated treatment outcomes in children (
N. Sesay +17 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Evaluating treatment outcomes stratified by regimen among drug-resistant TB patients in Sierra Leone
Public Health ActionSETTING: Sierra Leone has a high burden of drug-resistant TB (DR-TB), managed at three treatment centres. OBJECTIVE: To compare treatment success between BPaL (bedaquiline, pretomanid, and linezolid)/BPaLM (bedaquiline, pretomanid, linezolid, and ...
J.A. Koroma +21 more
doaj +1 more source
, 2017 Sorting is a crucial problem in data processing or database. Data processing will be more simple if the data has been sorted. Sorting problem requires special techniques to make the process of sorting faster.
Desiani, Anita +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source