Results 91 to 100 of about 30,121,162 (303)

Cervical Cancer Care Continuum in South India: Evidence from a Community-based Screening Program

Journal of Epidemiology and Global Health, 2019
In India, cervical cancer screening is conducted at various levels; however, after screening, the adherence to the cancer care continuum is barely understood.
E. Vidhubala, K. Niraimathi, Hemant Deepak Shewade, Sankar Mahadevan   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

TB disability and multimorbidity at the onset of treatment in Kenya, Uganda, Zambia and Zimbabwe

IJTLD Open
BACKGROUND: We evaluated the practicality of integrating assessments on the burden of multimorbidity (including disability) and the effectiveness of referral pathways at the start of TB treatment across Kenya, Uganda, Zambia and Zimbabwe.
The Kenya, Uganda, Zambia and Zimbabwe TB Disability Study Group listed by surname alphabetically:, S.A. Adakun, F.M. Banda, A. Bloom, M. Bochnowicz, J. Chakaya, R. Chimzizi, J.P. Dongo, C. Duri, A.D. Harries, I. Kathure, F.N. Kavenga, A.M.V. Kumar, Y. Lin, H. Luzze, I. Mbithi, M. Mputu, A. Mubanga, D. Mudoola, D. Nair, M. Ngwenya, S. Ntambi, P. Owiti, A. Owuor, P. Thekkur, C. Timire, E. Tweyongyere, M. YaDiul, R. Zachariah   +28 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Quality improvement package for severe tuberculosis triage in Tamil Nadu, India

Public Health Action
SETTING: Tamil Nadu Kasanoi Erappila Thittam (TN-KET) is a statewide differentiated tuberculosis (TB) care initiative to reduce TB deaths involving triaging for severe illness at diagnosis and referral of severely ill for appropriate inpatient care (2022–
A. Jeyakumar, S. Kalaiselvi, D. Nair, R. Vijayaprabha, K. Gayathri, D. Kabir, J.M. Melfha, T. Bhatnagar, R. Srinivasan, M. Balusamy, S Shanmugasundaram, Alicia Catherine, N Nithya, R Venkateshwar, A. Frederick, H.D. Shewade   +15 more
doaj   +1 more source

Data classification

, 2007
Title from PDF caption (viewed on Apr. 6, 2007).; Harvested from the web on 4/10/07This state policy is intended to provide a high-level data classification methodology to state agencies for the purpose of understanding and managing data and information ...
Ohio. Statewide IT Policy. Investment and Governance Division
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Enhancing parenteral therapy for anaemia among pregnant women in rural India

Public Health Action
SETTING: Primary care settings in a rural district of Telangana, India, under an anaemia control programme. OBJECTIVE: To explore the facilitators and barriers to parenteral iron therapy for moderate and severe anaemia, and possible solutions from the ...
P. Kotni, G. Ramaswamy, S. Cheela, S. Patil, P. Chinnakali, J.P. Tripathy, M. Khandale, D. Kamban, C. Konguvel, M. Manohar   +9 more
doaj   +1 more source

Tuberculosis screening among pregnant women attending a tertiary care hospital in Puducherry, South India: is it worth the effort?

Global Health Action, 2019
Background: The national tuberculosis (TB) programme in India recommends screening all pregnant women for TB, but this is rarely implemented. We carried out systematic TB screening among women attending the antenatal clinic of a tertiary care hospital in
Mathavaswami Vijayageetha, Ajay MV Kumar, Jayalakshmy Ramakrishnan, Sonali Sarkar, Dasari Papa, Kedar Mehta, Noyal M Joseph, Manju Rajaram, Sathish Rajaa, Palanivel Chinnakali   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source