Results 101 to 110 of about 6,219 (205)
Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release [PDF]
, 2017 Low pH-induced ligand release and receptor recycling are important steps for endocytosis. The transmembrane protein sortilin, a β-propeller containing endocytosis receptor, internalizes a diverse set of ligands with roles in cell differentiation and ...
Sub Crystal and Structural Chemistry +11 more
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Sortilin is dispensable for secondary injury processes following traumatic brain injury in mice
HeliyonTraumatic brain injury (TBI) is characterized by complex secondary injury processes involving the p75 neurotrophin receptor (p75NTR), which has been proposed as a possible therapeutic target.
Irina Staib-Lasarzik +6 more
doaj +1 more source
Sortilin and Homocysteine as Potential Biomarkers for Coronary Artery Diseases
International Journal of General Medicine, 2021 Rehab H Werida,1 Ayman Omran,2 Noha M El-Khodary1 1Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt; 2Department of Cardiology, Damanhour National Medical Institute, Damanhour ...
Werida RH, Omran A, El-Khodary NM
doaj
, 2022 Cancer is a disease in which cells within a particular part of the body grow and reproduce uncontrollably. Breast and lung cancer which are used as models within this study are two of the most common malignancies amongst the human population.
Giles, E.
core
Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF [PDF]
, 2015 Neurotrophic factors have been investigated in relation to depression. The aim of the present study was to widen this focus to sortilin, a receptor involved in neurotrophic signalling.
Gustafsen, C +10 more
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Expression of megalin, sortilin, and M6PR in human glomeruli.
, 2013 (A) Expression of megalin, M6PR, sortilin, podocin, nephrin, APN mRNAs by RT-PCR (+). Negative controls (−) run without RT enzyme. The marker used was 100 bp ladder.
Claus M. Petersen (343983) +8 more
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Effect of sortilin binding domain on APP lysosomal targeting.
, 2013 A: APP colocalization with lysosome. HEK293 cells were co-transfected with APP770-YFP and different sortilin constructs. The expressed APP and sortilin constructs excluding Sort-FL were visualized by either YFP or CFP fluorescence.
Swarna Lekha Vijayaraj (414076) +9 more
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Mapping sortilin binding to APP.
, 2013 (A) Identifying sortilin binding sites to APP. HEK293 cells were co-transfected with APP695-pcDNA3.1 (APP695) and Sort 78–385-CFP (lane 1) or Sort 385–786-CFP (lane 2), or Sort 756–831 (lane 3), or Sort 779–831-CFP (lane 4).
Swarna Lekha Vijayaraj (414076) +9 more
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A Potential Role for Sortilin in Lp(a) and Apo(a) Metabolism [PDF]
, 2018 Elevated levels of lipoprotein(a) (Lp(a)) are an independent, causal risk factor for coronary heart disease. Lp(a) is structurally similar to low-density lipoprotein (LDL), but is distinguished by the covalent addition of apolipoprotein(a) (apo(a ...
Gemin, Matthew
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