Results 91 to 100 of about 499,399 (313)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Size Matters in Conjugated Polymer Chirality‐Selective SWCNT Extraction

open access: yesAdvanced Science
Carbon‐based nanomaterials have catalyzed breakthroughs across various scientific and engineering disciplines. The key to unlocking a new generation of tailor‐made nanomaterials based on single‐walled carbon nanotubes (SWCNTs) lies in the precise sorting
Andrzej Dzienia   +7 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

House Price Fluctuations and Residential Sorting [PDF]

open access: yes
Empirical evidence indicates local jurisdictions are internally more heterogeneous than standard sorting models predict. We develop a dynamic multi-region model, with fluctuating regional house prices, where an owner-occupying household's location choice
Markus Haavio, Heikki Kauppi
core  

New methodology to optimize sorting in wood drying

open access: yesMaderas: Ciencia y Tecnología, 2014
One important problem in lumber drying is to maintain the lumber moisture content distribution within certain minimum and maximum values. Over-drying and under-drying are common causes for lower grade recovery and dimensional stability problems.
D. M. Elustondo   +2 more
doaj  

Pulse interference method against PRI sorting

open access: yesThe Journal of Engineering, 2019
Based on the purpose of proactive anti-reconnaissance, the essential characteristics of several typical pulse repetition interval (PRI) sorting algorithms were analysed and the feasibility of counter-deinterleaving was discussed.
Hao Nan   +3 more
doaj   +1 more source

Sorting with a popqueue

open access: yesRAIRO - Theoretical Informatics and Applications
We introduce a new sorting device for permutations, which we call popqueue. It consists of a special queue, having the property that any time one wants to extract elements from the queue, actually all the elements currently in the queue are poured into the output. We illustrate two distinct optimal algorithms, called Min and Cons, to sort a permutation
Cioni, Lapo, Ferrari, Luca
openaire   +2 more sources

Verification of Counting Sort and Radix Sort [PDF]

open access: yes, 2016
We discuss a mechanized correctness proof in KeY of Counting sort and Radix sort. Counting sort is an unusual sorting algorithm in the sense that it is based on arithmetic rather than comparisons. Radix sort is tailored to sorting arrays of large numbers.
C.P.T. de Gouw (Stijn)   +2 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy